|PRODUCT NAME||CATALOG #||UNIT||PRICE||QTY||FAVORITES|
|Roquefortine C||sc-202323||500 µg||$350.00||
Roquefortine C is a mycotoxin produced by Penicillium roqueforti and P. crustosum. This compound has been noted to cause serious toxic effects in cell lines. In some experiments, Roquefortine C has been used as a biomarker for penitrem A intoxication. Studies suggest that G protein-mediated signaling is a key component of Roquefortine C production by Penicillium roqueforti. Further experiments report that Roquefortine C is potentially a neurotoxic compound that activates and inhibits detoxification enzymes Mdr (P-glycoprotein, P-gp) and CYP (cytochrome P450-3A), respectively.
1. Keblys, M., et al. 2004. Mycopathologia. 158: 317-324. PMID: 15702270
2. Bünger, J., et al. 2004. Toxicology. 202: 199-211. PMID: 15337583
3. Aninat, C., et al. 2005. Food Addit Contam. 22: 361-368. PMID: 16019806
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5. Tiwary, A.K., et al. 2009. J. Vet. Diagn. Invest. 21: 237-239. PMID: 19286504
See how others have used Roquefortine C. Click on the entry to view the PubMed entry .
PMID: # 25580944
Cakmakci, S. et al. 2015. Mycotoxin production capability of Penicillium roqueforti in strains isolated from mould-ripened traditional Turkish civil cheese. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 32: 245-9.
PMID: # 23127715
Cakmakci, S. et al. 2012. Morphological, molecular, and mycotoxigenic identification of dominant filamentous fungi from moldy civil cheese. Journal of food protection. 75: 2045-9.
PMID: # 15958659
Rand, TG. et al. 2005. Inflammatory and cytotoxic responses in mouse lungs exposed to purified toxins from building isolated Penicillium brevicompactum Dierckx and P. chrysogenum Thom. Toxicol. Sci.. 87: 213-222.
PMID: # 2730153
Frisvad, JC. et al. 1989 May-Jun. Analysis and screening for mycotoxins and other secondary metabolites in fungal cultures by thin-layer chromatography and high-performance liquid chromatography. Arch. Environ. Contam. Toxicol.. 18: 331-335.
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