Date published: 2026-2-24

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Protoporphyrin IX disodium salt (CAS 50865-01-5)

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Alternate Names:
Ooporphyrin disodium salt; Zinc ionophore II; 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid disodium salt
Application:
Protoporphyrin IX disodium salt is a soluble GCS(guanylate cyclase) activator
CAS Number:
50865-01-5
Molecular Weight:
606.62
Molecular Formula:
C34H32N4O42Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Protoporphyrin IX disodium salt is a porphyrin-based natural product that serves as a starting material for the biosynthesis of chlorophyll and heme.


Protoporphyrin IX disodium salt (CAS 50865-01-5) References

  1. Porphyrins and porphines inhibit the ribonuclease P reaction in vitro.  |  Hori, Y., et al. 2002. Nucleic Acids Res Suppl. 111-2. PMID: 12903130
  2. Sonodynamic effects of protoporphyrin IX disodium salt on isolated sarcoma 180 cells.  |  Liu, Q., et al. 2006. Ultrasonics. 45: 56-60. PMID: 16890264
  3. Comparison between sonodynamic effect with protoporphyrin IX and hematoporphyrin on sarcoma 180.  |  Liu, Q., et al. 2007. Cancer Chemother Pharmacol. 60: 671-80. PMID: 17219011
  4. Sonodynamic antitumor effect of protoporphyrin IX disodium salt on S180 solid tumor.  |  Liu, Q., et al. 2007. Chemotherapy. 53: 429-36. PMID: 17952003
  5. Study of cell killing effect on S180 by ultrasound activating protoporphyrin IX.  |  Wang, XB., et al. 2008. Ultrasonics. 48: 135-40. PMID: 18068747
  6. Inhibition of hepadnavirus reverse transcriptase-epsilon RNA interaction by porphyrin compounds.  |  Lin, L. and Hu, J. 2008. J Virol. 82: 2305-12. PMID: 18094191
  7. Sonodynamic effects of protoporphyrin IX disodium salt on Ehrlich ascetic tumor cells.  |  Wang, P., et al. 2010. Ultrasonics. 50: 634-8. PMID: 20189622
  8. Rapid simultaneous determination of protoporphyrin IX, uroporphyrin III and coproporphyrin III in human whole blood by non-linear variable-angle synchronous fluorescence technique coupled with partial least squares.  |  Huang, W., et al. 2010. Talanta. 82: 1516-20. PMID: 20801366
  9. Structure of glutathione S-transferase 1 from the major human hookworm parasite Necator americanus (Na-GST-1) in complex with glutathione.  |  Asojo, OA. and Ceccarelli, C. 2014. Acta Crystallogr F Struct Biol Commun. 70: 1162-6. PMID: 25195885
  10. Sonodynamic therapy induces apoptosis of human leukemia HL-60 cells in the presence of protoporphyrin IX.  |  Su, X., et al. 2016. Gen Physiol Biophys. 35: 155-64. PMID: 26891272
  11. Unravel the interaction of protoporphyrin IX with reduced graphene oxide by vital spectroscopic techniques.  |  Jhonsi, MA., et al. 2017. Spectrochim Acta A Mol Biomol Spectrosc. 178: 86-93. PMID: 28167363
  12. Photoelectron spectroscopy of the protoporphyrin IX dianion.  |  Gibbard, JA., et al. 2021. Phys Chem Chem Phys. 23: 18425-18431. PMID: 34612383
  13. The ratio of erythrocyte zinc-protoporphyrin to protoporphyrin IX in disease and its significance in the mechanism of lead toxicity on haem synthesis.  |  Nelson, JC., et al. 1998. Ann Clin Biochem. 35 (Pt 3): 422-6. PMID: 9635110

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Protoporphyrin IX disodium salt, 250 mg

sc-258048
250 mg
$58.00

Protoporphyrin IX disodium salt, 1 g

sc-258048A
1 g
$177.00

Protoporphyrin IX disodium salt, 5 g

sc-258048B
5 g
$747.00