Date published: 2025-11-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

Protoporphyrin IX dimethyl ester (CAS 6164-53-0)

0.0(0)
Write a reviewAsk a question

Application:
Protoporphyrin IX dimethyl ester is a porphyrin and iron chelator
CAS Number:
6164-53-0
Molecular Weight:
590.71
Molecular Formula:
C36H38N4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Protoporphyrin IX dimethyl ester is a derivative of protoporphyrin IX, a key intermediate in the heme biosynthetic pathway. It is involved in the formation of heme, a component of hemoglobin and other hemoproteins. Protoporphyrin IX dimethyl ester is a porphyrin compound, characterized by its tetrapyrrole ring structure. It plays a vital role in the transportation and storage of oxygen, as it is a fundamental component of hemoglobin. Protoporphyrin IX dimethyl ester is involved in various enzymatic reactions. Its structure and properties make it an important molecule in the study of heme biosynthesis and related metabolic pathways.


Protoporphyrin IX dimethyl ester (CAS 6164-53-0) References

  1. Dimethyl propionate ester heme-containing cytochrome b5: structure and stability.  |  Banci, L., et al. 2001. J Biol Inorg Chem. 6: 490-503. PMID: 11472013
  2. A comparison of protoporphyrin IX and protoporphyrin IX dimethyl ester as a photosensitizer in poorly differentiated human nasopharyngeal carcinoma cells.  |  Yee, KK., et al. 2002. Photochem Photobiol. 76: 678-82. PMID: 12511050
  3. A modified procedure for the preparation of protoporphyrin IX dimethyl ester from hemoglobin.  |  CHU, EJ. 1946. J Biol Chem. 163: 713. PMID: 20985643
  4. Chlorin photosensitizers sterically designed to prevent self-aggregation.  |  Uchoa, AF., et al. 2011. J Org Chem. 76: 8824-32. PMID: 21932835
  5. Observation of heme transfer from cytochrome b5 to DNA aptamer.  |  Lin, YW., et al. 2012. Spectrochim Acta A Mol Biomol Spectrosc. 96: 365-9. PMID: 22717695
  6. Antioxidative effect of several porphyrins on lipid peroxidation in rat liver homogenates.  |  Imai, K., et al. 1990. Chem Pharm Bull (Tokyo). 38: 258-60. PMID: 2337947
  7. Heck coupling of olefins to mixed methyl/thienyl monolayers on Si(111) surfaces.  |  O'Leary, LE., et al. 2013. J Am Chem Soc. 135: 10081-90. PMID: 23802505
  8. Iron nitrosyl 'natural' porphyrinates: does the porphyrin matter?  |  Wyllie, GR., et al. 2014. Inorg Chem. 53: 3763-8. PMID: 24620710
  9. Synthesis of new chlorin e6 trimethyl and protoporphyrin IX dimethyl ester derivatives and their photophysical and electrochemical characterizations.  |  Menezes, JC., et al. 2014. Chemistry. 20: 13644-55. PMID: 25171181
  10. Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.  |  Gibault, F., et al. 2017. ChemMedChem. 12: 954-961. PMID: 28334506
  11. Synthesis and Characterization of Temperature-Sensitive and Chemically Cross-Linked Poly(N-isopropylacrylamide)/Photosensitizer Hydrogels for Applications in Photodynamic Therapy.  |  Belali, S., et al. 2018. Biomacromolecules. 19: 1592-1601. PMID: 29596749
  12. Effects of TONS504-photodynamic therapy on mouse mammary tumor cells.  |  Osaki, T., et al. 2018. Oncol Lett. 16: 2078-2084. PMID: 30008903
  13. Thermodynamics of ligand and oxygen binding to cobalt protoporphyrin IX dimethyl ester in toluene solution.  |  Stynes, DV., et al. 1973. J Am Chem Soc. 95: 1796-801. PMID: 4689919
  14. The purification of protoporphyrin IX and protoporphyrin IX dimethyl ester with Avicel-SF and chromagram sheet.  |  Russell, CS. 1966. J Chromatogr. 25: 163-4. PMID: 5971556
  15. The effect of the irradiation wavelength on the processes sensitized by protoporphyrin IX dimethyl ester.  |  Kubát, P., et al. 1997. Radiat Res. 148: 382-5. PMID: 9339954

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Protoporphyrin IX dimethyl ester, 100 mg

sc-264152
100 mg
$190.00

Protoporphyrin IX dimethyl ester, 500 mg

sc-264152A
500 mg
$650.00