POBN A cell permeable hydrophilic spin trap

POBN  (CAS 66893-81-0)

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Synonym: α-(4-Pyridyl 1-oxide)-N-tert-butylnitrone
Application: A cell permeable hydrophilic spin trap
CAS Number: 66893-81-0
Purity: ≥98%
Molecular Weight: 194.23
Molecular Formula: C10H14N2O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

POBN sc-203201 500 mg $145.00
POBN sc-203201A 1 g $267.00

POBN is a cell permeable hydrophilic spin trap for in vitro studies. Water soluble analog of PBN. Low paramagnetic impurities. No further purification required.


Two decades of spin trapping: E.G. Janzen & D.L. Hare; Adv. Radic. Chem. 1, 253 (1990) In vitro and in vivo evidence for the formation of methyl radical from procarbazine: a spin-trapping study: L. Goria-Gatti, et al.; Carcinogenesis 13, 799 (1992) Polyunsaturated fatty acids increase lipid radical formation induced by oxidant stress in endothelial cells: L.S. Alexander-North, et al.; J. Lipid Res. 35, 1773 (1994) The spin trap alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone stimulates peroxidase-mediated oxidation of deferoxamine. Implications for pharmacological use of spin-trapping agents: M.L. McCormick, et al.; J. Biol. Chem. 270, 29265 (1995) Identification of free radical formation and F2-isoprostanes in vivo by acute Cr(VI) poisoning: M.B. Kadiiska, et al.; Chem. Res. Toxicol. 11, 1516 (1998) Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes: K. Stadler, et al.; Free Radic. Biol. Med. 45, 866 (2008)

Physical State :
Solubility :
Solubility: Soluble in DMSO, water, methanol or 100% ethanol.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

Download SDS (MSDS)

Certificate of Analysis

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