Date published: 2025-10-3

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Pinostrobin (CAS 480-37-5)

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Alternate Names:
(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
CAS Number:
480-37-5
Purity:
≥98%
Molecular Weight:
270.28
Molecular Formula:
C16H14O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pinostrobin compound has garnered significant attention in scientific research. Recent studies have explored various aspects of pinostrobin, including synthesis methods, scientific applications, mechanisms of action, biochemical and physiological effects, advantages and limitations in lab experiments, as well as future directions for its utilization. its anti-inflammatory properties have been studied for their potential in alleviating inflammation. Additionally, pinostrobin has shown antibacterial effects, providing a potential avenue for combating bacterial infections. Pinostrobin functions as an antioxidant by scavenging free radicals and reducing oxidative stress within cells.


Pinostrobin (CAS 480-37-5) References

  1. Protective effects of pinostrobin on β-amyloid-induced neurotoxicity in PC12 cells.  |  Xian, YF., et al. 2012. Cell Mol Neurobiol. 32: 1223-30. PMID: 22565301
  2. The antiproliferative effect of pinostrobin on human umbilical vein endothelial cells (HUVEC).  |  Siekmann, TR., et al. 2013. Eur Rev Med Pharmacol Sci. 17: 668-72. PMID: 23543451
  3. Inhibitory effect of pinostrobin from Renealmia alpinia, on the enzymatic and biological activities of a PLA2.  |  Gómez-Betancur, I., et al. 2016. Int J Biol Macromol. 89: 35-42. PMID: 27109758
  4. Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells.  |  Gao, WY., et al. 2018. J Agric Food Chem. 66: 6083-6093. PMID: 29862818
  5. Acacetin and Pinostrobin Inhibit Malignant Breast Epithelial Cell Adhesion and Focal Adhesion Formation to Attenuate Cell Migration.  |  Jones, AA. and Gehler, S. 2020. Integr Cancer Ther. 19: 1534735420918945. PMID: 32493139
  6. The Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Pinostrobin in Rats: Ultra-High-Performance Liquid Chromatography Coupled With Linear Trap Quadrupole Orbitrap Mass Spectrometry Studies.  |  Sun, X., et al. 2020. Front Pharmacol. 11: 574638. PMID: 33324207
  7. Acacetin and pinostrobin as a promising inhibitor of cancer-associated protein kinases.  |  Singh, S., et al. 2021. Food Chem Toxicol. 151: 112091. PMID: 33647348
  8. Pinostrobin inhibits proliferation and induces apoptosis in cancer stem-like cells through a reactive oxygen species-dependent mechanism.  |  Jadaun, A., et al. 2019. RSC Adv. 9: 12097-12109. PMID: 35516989
  9. Study of the dermal anti-inflammatory, antioxidant, and analgesic activity of pinostrobin.  |  González, AS., et al. 2022. Heliyon. 8: e10413. PMID: 36097473
  10. Discovery of Pinostrobin as a Melanogenic Agent in cAMP/PKA and p38 MAPK Signaling Pathway.  |  Yoon, JH., et al. 2022. Nutrients. 14: PMID: 36145089
  11. Pinostrobin: An Adipogenic Suppressor from Fingerroot (Boesenbergia rotunda) and Its Possible Mechanisms.  |  San, HT., et al. 2022. Foods. 11: PMID: 36230099
  12. Pinostrobin ameliorates lipopolysaccharide (LPS)-induced inflammation and endotoxemia by inhibiting LPS binding to the TLR4/MD2 complex.  |  Athapaththu, AMGK., et al. 2022. Biomed Pharmacother. 156: 113874. PMID: 36270256
  13. Pinostrobin Suppresses the α-Melanocyte-Stimulating Hormone-Induced Melanogenic Signaling Pathway.  |  Athapaththu, AMGK., et al. 2023. Int J Mol Sci. 24: PMID: 36614262
  14. Pinostrobin alleviates chronic restraint stress‑induced cognitive impairment by modulating oxidative stress and the function of astrocytes in the hippocampus of rats.  |  Thongrong, S., et al. 2023. Biomed Rep. 18: 20. PMID: 36798091
  15. Pinostrobin from Boesenbergia rotunda attenuates oxidative stress and promotes functional recovery in rat model of sciatic nerve crush injury.  |  Kongsui, R., et al. 2023. Braz J Med Biol Res. 56: e12578. PMID: 36856256

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pinostrobin, 5 mg

sc-236401
5 mg
$286.00