Date published: 2025-11-20

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Pigment Yellow 12 (CAS 6358-85-6)

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Alternate Names:
Benzidine Yellow
CAS Number:
6358-85-6
Molecular Weight:
629.49
Molecular Formula:
C32H26Cl2N6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pigment Yellow 12 operates by absorbing and releasing light at precise wavelengths, thereby enabling it to serve as an excellent fluorescent tool for biological imaging purposes. By stimulating it with a particular light wavelength, the pigment absorbs the energy and subsequently emits light at a lengthier wavelength. This emitted light can be conveniently detected and visualized through the utilization of a fluorescence microscope, facilitating various applications in biological imaging.


Pigment Yellow 12 (CAS 6358-85-6) References

  1. Erratum: DNA damage in isolated rat hepatocytes exposed to C.I. pigment orange 5 and C.I. pigment yellow 12 by the alkaline comet assay; peter moller, Hakan wallin, niels grunnet, lotte risom, and lisbeth E. Knudsen; teratogenesis, carcinogenesis, and mutagenesis 18: 9-16 (1998).  |  Moller, P. 2001. Teratog Carcinog Mutagen. 21: 107. PMID: 11135325
  2. Sensitization to azo dyes: negative patch tests to yellow and red azo dyes in printed paper.  |  Thierbach, MA., et al. 1992. Contact Dermatitis. 27: 22-6. PMID: 1424587
  3. Carcinogenicity of azo colorants: influence of solubility and bioavailability.  |  Golka, K., et al. 2004. Toxicol Lett. 151: 203-10. PMID: 15177655
  4. Crystal engineering on industrial diaryl pigments using lattice energy minimizations and X-ray powder diffraction.  |  Schmidt, MU., et al. 2007. J Phys Chem B. 111: 9722-32. PMID: 17672490
  5. Mutagenicity of benzidine and benzidine-congener dyes and selected monoazo dyes in a modified Salmonella assay.  |  Prival, MJ., et al. 1984. Mutat Res. 136: 33-47. PMID: 6371512
  6. Fate of water-insoluble and water-soluble dichlorobenzidine-based pigments in Fisher 344 rats.  |  Decad, GM., et al. 1983. J Toxicol Environ Health. 11: 455-65. PMID: 6842621
  7. Analysis, purification and stability: requirements for a metabolism study of an azo dye and pigment.  |  Nony, CR. and Bowman, MC. 1980. J Anal Toxicol. 4: 63-7. PMID: 7191457
  8. Trace analysis of potentially carcinogenic metabolites of an azo dye and pigment in hamster and human urine as determined by two chromatographic procedures.  |  Nony, CR. and Bowman, MC. 1980. J Chromatogr Sci. 18: 64-74. PMID: 7372761
  9. DNA damage in isolated rat hepatocytes exposed to C.I. pigment orange 5 and C.I. pigment yellow 12 by the alkaline comet assay.  |  Møller, P., et al. 1998. Teratog Carcinog Mutagen. 18: 9-16. PMID: 9586766
  10. The mutagenicity of some of the proposed metabolites of direct black 38 and pigment yellow 12 IN THE Salmonella typhimurium assay system  |  EJ Lazear, JG Shaddock, PR Barren, SC Louie. 1979. Toxicology Letters. Volume 4, Issue 6: 519-525.
  11. Improvement of Dye Properties of the Azo Pigment Yellow 12 Using a Micromixer-Based Process  |  Helmut Pennemann, Stephan Forster, Joachim Kinkel, Volker Hessel, Holger Löwe, and Li Wu. 2005. Org. Process Res. Dev. 9, 2: 188–192.
  12. Preparation and characterization of encapsulated C.I. pigment yellow 12 via ball-milling and mini-emulsion polymerization  |  Yongyue Ding, Mingquan Ye, Aijun Han, Yao Zang. 2018. Progress in Organic Coatings. 117: 69-75.
  13. High-Flux Continuous-Flow Synthesis of C.I. Pigment Yellow 12 from Clear Alkaline Solutions of the Coupling Component  |  Zhiping Shi, Xudong Wang, Defei Yin, Wei Li, Dongzhi Liu, and Xueqin Zhou. 2022. Org. Process Res. Dev. 26, 3: 661–669.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pigment Yellow 12, 1 g

sc-491787
1 g
$152.00

Pigment Yellow 12, 5 g

sc-491787A
5 g
$496.00