Molecular structure of Phentolamine hydrochloride, CAS Number: 73-05-2
Phentolamine hydrochloride (CAS 73-05-2)
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Alternate Names:
2-[N-(m-Hydroxyphenyl)-p-toluidinomethyl]imidazoline Hydrochloride; 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-phenol Hydrochloride
Application:
Phentolamine hydrochloride is an a-Adrenergic blocker
CAS Number:
73-05-2
Purity:
≥98%
Molecular Weight:
317.81
Molecular Formula:
C17H19N3O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Phentolamine hydrochloride is a reversible nonselective alpha-adrenergic antagonist that works by blocking the action of norepinephrine at alpha receptors. It is used to study the effects of adrenergic agonists and antagonists on various physiological processes. Phentolamine hydrochloride is particularly useful in investigating the role of the sympathetic nervous system in regulating blood pressure, heart rate, and other cardiovascular functions. Its ability to block alpha receptors provides clarity in understanding the mechanisms underlying sympathetic nervous system activity. Phentolamine hydrochloride is an important pharmacological agent in biochemistry, providing insights into the physiological and pharmacological effects of adrenergic receptor modulation.
Phentolamine hydrochloride (CAS 73-05-2) References
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- Autonomic Receptors and Nitric-Oxide Involvements in Mediating Vasorelaxation Effect Induced by Syzygium polyanthum Leaves Extract. | Ismail, A. and Wan Ahmad, WAN. 2017. Pharmacognosy Res. 9: S9-S14. PMID: 29333036
- The Octopamine Receptor Is a Possible Target for Eugenol-Induced Hyperactivity in the Blood-Sucking Bug Triatoma infestans (Hemiptera: Reduviidae). | Reynoso, MMN., et al. 2020. J Med Entomol. 57: 627-630. PMID: 31637445
- Degradation kinetics of phentolamine hydrochloride in solution. | Wang, DP., et al. 1988. J Pharm Sci. 77: 972-6. PMID: 3225760
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- Plasmodium berghei-induced malaria decreases pain sensitivity in mice. | Oyewole, AL., et al. 2021. Onderstepoort J Vet Res. 88: e1-e18. PMID: 33567845
- Spinal neurochemical mechanisms of acute stress-induced visceral hypersensitivity in healthy rats. | Ness, TJ., et al. 2022. Neurosci Lett. 770: 136401. PMID: 34929317
- The role of serotonergic and catecholaminergic systems for possible antidepressant activity of apigenin. | Al-Yamani, MJ., et al. 2022. Saudi J Biol Sci. 29: 11-17. PMID: 35002391
- Effects of dibenzylbutyrolactone lignans arctigenin and trachelogenin on the motility of isolated rat ileum. | Koech, PK., et al. 2022. Toxicol Rep. 9: 1222-1232. PMID: 36518476
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AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Phentolamine hydrochloride, 50 mg | sc-205802 | 50 mg | $81.00 | |||
Phentolamine hydrochloride, 100 mg | sc-205802A | 100 mg | $146.00 | |||
Phentolamine hydrochloride, 250 mg | sc-205802B | 250 mg | $226.00 | |||
Phentolamine hydrochloride, 500 mg | sc-205802C | 500 mg | $400.00 | |||
Phentolamine hydrochloride, 1 g | sc-205802D | 1 g | $768.00 | |||
Phentolamine hydrochloride, 2 g | sc-205802E | 2 g | $1430.00 | |||
Phentolamine hydrochloride, 2.5 g | sc-205802F | 2.5 g | $1737.00 |