Date published: 2025-10-16

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Perilla Ketone (CAS 553-84-4)

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Alternate Names:
1-(3-Furanyl)-4-methyl-1-pentanone; 1-(3-Furyl)-4-methyl-1-pentanone; 3-(4-Methylpentanoyl)furan; NSC 348407
Application:
Perilla Ketone is a potent pulmonary edemagenic agent for laboratory animals.
CAS Number:
553-84-4
Purity:
≥98%
Molecular Weight:
166.22
Molecular Formula:
C10H14O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Perilla Ketone is a potent pulmonary edemagenic agent for laboratory animals. Perilla ketone (PK) is a natural compound derived from the essential oils of the Perilla frutescens plant, which belongs to the mint family. It possesses several medicinal and properties, being colorless, and odorless. Extensive scientific research has explored the diverse applications of Perilla ketone.


Perilla Ketone (CAS 553-84-4) References

  1. Determination of toxic perilla ketone, secondary plant metabolites and antioxidative capacity in five Perilla frutescens L. varieties.  |  Müller-Waldeck, F., et al. 2010. Food Chem Toxicol. 48: 264-70. PMID: 19833165
  2. Characteristic aroma-active compounds of Korean perilla (Perilla frutescens Britton) leaf.  |  Seo, WH. and Baek, HH. 2009. J Agric Food Chem. 57: 11537-42. PMID: 20000853
  3. Bovine atypical interstitial pneumonia.  |  Doster, AR. 2010. Vet Clin North Am Food Anim Pract. 26: 395-407. PMID: 20619192
  4. GC-MS analysis of volatile compounds of Perilla frutescens Britton var. Japonica accessions: Morphological and seasonal variability.  |  Ghimire, BK., et al. 2017. Asian Pac J Trop Med. 10: 643-651. PMID: 28870340
  5. Preparative Separation of Three Monoterpenes from Perilla frutescens var. crispa Using Centrifugal Partition Chromatography.  |  Nam, B., et al. 2019. Int J Anal Chem. 2019: 8751345. PMID: 30728839
  6. Morphology of noncardiogenic pulmonary edema induced by Perilla ketone in sheep.  |  Guerry-Force, ML., et al. 1988. Am J Pathol. 133: 285-97. PMID: 3189507
  7. Advances in the Pharmacological Activities and Effects of Perilla Ketone and Isoegomaketone.  |  Wang, R., et al. 2022. Evid Based Complement Alternat Med. 2022: 8809792. PMID: 36337585
  8. Perilla ketone: a model of increased pulmonary microvascular permeability pulmonary edema in sheep.  |  Coggeshall, JW., et al. 1987. Am Rev Respir Dis. 136: 1453-8. PMID: 3688648
  9. Species susceptibility to the pulmonary toxicity of 3-furyl isoamyl ketone (perilla ketone): in vivo support for involvement of the lung monooxygenase system.  |  Garst, JE., et al. 1985. J Anim Sci. 60: 248-57. PMID: 3972746
  10. Perilla ketone toxicity: a chemical model for the study of equine restrictive lung disease.  |  Breeze, RG., et al. 1984. Equine Vet J. 16: 180-4. PMID: 6734583
  11. Perilla ketone increases endothelial cell monolayer permeability in vitro.  |  Waters, CM., et al. 1993. J Appl Physiol (1985). 74: 2493-501. PMID: 7687599
  12. Evaluation of perilla ketone-induced unilateral lung injury using external gamma scanning.  |  Abernathy, VJ., et al. 1994. J Appl Physiol (1985). 76: 138-45. PMID: 8175497
  13. Perilla ketone: a potent lung toxin from the mint plant, Perilla frutescens Britton.  |  Wilson, BJ., et al. 1977. Science. 197: 573-4. PMID: 877573

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Perilla Ketone, 25 mg

sc-478902
25 mg
$347.00