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Palustric Acid (CAS 1945-53-5)

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Alternate Names:
Palustric Acid is known as a component of pine oleoresin.
Application:
Palustric Acid is an abietane-type of diterpene resin acid and has antibacterial, cardiovascular, and antioxidant properties.
CAS Number:
1945-53-5
Molecular Weight:
302.45
Molecular Formula:
C20H30O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Palustric Acid is one of the components of pine oleoresin. Palustric Acid is an abietane-type of diterpene resin acid and has antibacterial and antioxidant porperties. The typical double bonds in palustric acid are in the cis configuration, which is common in unsaturated fatty acids and impacts the fluidity and flexibility of the fatty acid. Polyunsaturated fatty acids like palustric acid are components of cell membranes. They contribute to the fluidity and flexibility of the membranes, which are essential for proper cellular function, communication, and the ability to adapt to changing temperatures. The susceptibility to oxidation is a concern with polyunsaturated fatty acids, including palustric acid. Oxidation can lead to the formation of harmful compounds.


Palustric Acid (CAS 1945-53-5) References

  1. Separation of resin acids using cyclodextrin-modified capillary electrophoresis.  |  Luong, JH., et al. 1999. Electrophoresis. 20: 1546-54. PMID: 10424479
  2. Release of intermediate reactive hydrogen peroxide by macrophage cells activated by natural products.  |  Moreira, RR., et al. 2001. Biol Pharm Bull. 24: 201-4. PMID: 11217094
  3. Significance of wood terpenoids in the resistance of Scots pine provenances against the old house borer, Hylotrupes bajulus, and brown-rot fungus, Coniophora puteana.  |  Nerg, AM., et al. 2004. J Chem Ecol. 30: 125-41. PMID: 15074661
  4. A cytochrome P450 involved in the metabolism of abietane diterpenoids by Pseudomonas abietaniphila BKME-9.  |  Smith, DJ., et al. 2004. J Bacteriol. 186: 3631-9. PMID: 15150251
  5. A large gene cluster in Burkholderia xenovorans encoding abietane diterpenoid catabolism.  |  Smith, DJ., et al. 2007. J Bacteriol. 189: 6195-204. PMID: 17586638
  6. Distinct roles for two CYP226 family cytochromes P450 in abietane diterpenoid catabolism by Burkholderia xenovorans LB400.  |  Smith, DJ., et al. 2008. J Bacteriol. 190: 1575-83. PMID: 18156276
  7. Cytotoxicity of active ingredients extracted from plants of the Brazilian 'Cerrado'.  |  Soares, VC., et al. 2011. Nat Prod Commun. 6: 983-4. PMID: 21834238
  8. Modularity of Conifer Diterpene Resin Acid Biosynthesis: P450 Enzymes of Different CYP720B Clades Use Alternative Substrates and Converge on the Same Products.  |  Geisler, K., et al. 2016. Plant Physiol. 171: 152-64. PMID: 26936895
  9. Identification and Quantitative Determination of Resin Acids from Corsican Pinus pinaster Aiton Oleoresin Using 13 C-NMR Spectroscopy.  |  Ottavioli, J., et al. 2019. Chem Biodivers. 16: e1800482. PMID: 30632681
  10. Functions of mountain pine beetle cytochromes P450 CYP6DJ1, CYP6BW1 and CYP6BW3 in the oxidation of pine monoterpenes and diterpene resin acids.  |  Chiu, CC., et al. 2019. PLoS One. 14: e0216753. PMID: 31071168
  11. Resource partitioning to growth, storage and defence in nitrogen-fertilized Scots pine and susceptibility of the seedlings to the tarnished plant bug Lygus rugulipennis.  |  Holopainen, JK., et al. 1995. New Phytol. 131: 521-532. PMID: 33863121
  12. Measurement and Prediction of Isothermal Vapor-Liquid Equilibrium and Thermodynamic Properties of a Turpentine + Rosin System Using the COSMO-RS Model.  |  Li, Y., et al. 2022. ACS Omega. 7: 16270-16277. PMID: 35601293
  13. Ultra High-Performance Supercritical Fluid Chromatography for the Quantitation of Diterpene Resin Acids in Norway Spruce Samples.  |  Goels, T., et al. 2022. Front Pharmacol. 13: 906411. PMID: 35770082
  14. Inhibition of platelet aggregation by diterpene acids from Pinus massoniana resin.  |  Cheung, HT., et al. 1994. Arzneimittelforschung. 44: 17-25. PMID: 8135873

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Palustric Acid, 2.5 mg

sc-478082
2.5 mg
$357.00

Palustric Acid, 25 mg

sc-478082A
25 mg
$717.00

Palustric Acid, 100 mg

sc-478082B
100 mg
$1132.00

Palustric Acid, 250 mg

sc-478082C
250 mg
$1543.00