Molecular structure of Neohesperidin dihydrochalcone, CAS Number: 20702-77-6
Neohesperidin dihydrochalcone (CAS 20702-77-6)
Alternate Names:
1-(4-((2-O-[6-Deoxy-α-L-mannopyranosyl]-β-D-glucopyranosyl)oxy)-2,6-dihydroxyphenyl)-3-[3-hydroxy-4-methoxyphenyl]-1-propanone
Application:
Neohesperidin dihydrochalcone is a flavonoid sweetening agent with potent antioxidant activity
CAS Number:
20702-77-6
Purity:
≥95%
Molecular Weight:
612.58
Molecular Formula:
C28H36O15
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Neohesperidin dihydrochalcone is a flavonoid sweetening agent with potent antioxidant activity.
Neohesperidin dihydrochalcone (CAS 20702-77-6) References
- Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death. | Choi, JM., et al. 2007. Biol Pharm Bull. 30: 324-30. PMID: 17268074
- Application of a liquid chromatography-tandem mass spectrometry method to the pharmacokinetics, bioavailability and tissue distribution of neohesperidin dihydrochalcone in rats. | Wang, X., et al. 2014. Xenobiotica. 44: 555-61. PMID: 24274324
- Effect of neohesperidin dihydrochalcone on the activity and stability of alpha-amylase: a comparative study on bacterial, fungal, and mammalian enzymes. | Kashani-Amin, E., et al. 2015. J Mol Recognit. 28: 605-13. PMID: 25808616
- Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice. | Shi, Q., et al. 2015. Int Immunopharmacol. 29: 722-729. PMID: 26362205
- Neohesperidin dihydrochalcone down-regulates MyD88-dependent and -independent signaling by inhibiting endotoxin-induced trafficking of TLR4 to lipid rafts. | Xia, X., et al. 2015. Free Radic Biol Med. 89: 522-32. PMID: 26453923
- Novel Neohesperidin Dihydrochalcone Analogue Inhibits Adipogenic Differentiation of Human Adipose-Derived Stem Cells through the Nrf2 Pathway. | Han, GE., et al. 2018. Int J Mol Sci. 19: PMID: 30060630
- Effect of different concentrations of neohesperidin dihydrochalcone on performance, egg quality, serum biochemistry and intestinal morphology in laying hens. | Zhu, AN., et al. 2021. Poult Sci. 100: 101097. PMID: 34049213
- Effects of Neohesperidin Dihydrochalcone (NHDC) on Oxidative Phosphorylation, Cytokine Production, and Lipid Deposition. | Choi, S., et al. 2021. Foods. 10: PMID: 34207068
- Neohesperidin Dihydrochalcone and Neohesperidin Dihydrochalcone-O-Glycoside Attenuate Subcutaneous Fat and Lipid Accumulation by Regulating PI3K/AKT/mTOR Pathway In Vivo and In Vitro. | Kwon, M., et al. 2022. Nutrients. 14: PMID: 35268062
- Development of a HPLC-UV Method for the Separation and Quantification of Hesperidin, Neohesperidin, Neohesperidin Dihydrochalcone and Hesperetin. | Chen, L., et al. 2023. Nat Prod Res. 37: 1714-1718. PMID: 35915890
- In vitro and in silico perspectives on the activation of antioxidant responsive element by citrus-derived flavonoids. | Guan, T., et al. 2023. Front Nutr. 10: 1257172. PMID: 37674886
- Modeling the structure of the transmembrane domain of T1R3, a subunit of the sweet taste receptor, with neohesperidin dihydrochalcone using molecular dynamics simulation. | Nakagita, T., et al. 2023. Biosci Biotechnol Biochem. 87: 1470-1477. PMID: 37715303
- A combination of rebaudioside A and neohesperidin dihydrochalcone suppressed weight gain by regulating visceral fat and hepatic lipid metabolism in ob/ob mice. | Kim, Y., et al. 2024. Food Sci Biotechnol. 33: 913-923. PMID: 38371686
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Neohesperidin dihydrochalcone, 1 g | sc-219345 | 1 g | $117.00 | |||
Neohesperidin dihydrochalcone, 5 g | sc-219345A | 5 g | $535.00 |