Date published: 2025-10-15

1-800-457-3801

SCBT Portrait Logo
Seach Input

N,N-Dimethyldodecylamine N-oxide (CAS 1643-20-5)

5.0(1)
Write a reviewAsk a question

Alternate Names:
Lauryldimethylamine N-oxide
Application:
N,N-Dimethyldodecylamine N-oxide is a non-ionic detergent
CAS Number:
1643-20-5
Purity:
≥94%
Molecular Weight:
229.40
Molecular Formula:
C14H31NO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

N,N-Dimethyldodecylamine N-oxide (DDAO) is a quaternary ammonium compound widely used in scientific research for its surfactant properties and versatile applications. DDAO acts as a detergent due to its amphiphilic nature, possessing both hydrophobic and hydrophilic regions in its molecular structure. In research, DDAO is primarily utilized in biochemical and biophysical studies, particularly in membrane protein research. Its ability to solubilize and stabilize membrane proteins makes it invaluable for various applications, including protein extraction, purification, and crystallization. Moreover, DDAO is frequently employed as a detergent in cell lysis protocols, aiding in the isolation of intact proteins from biological samples. Its surfactant properties also find applications in analytical techniques such as liquid chromatography and mass spectrometry, where it assists in sample preparation and analyte solubilization. Furthermore, DDAO has been investigated in environmental research for its role in enhancing the biodegradation of organic pollutants and improving the remediation of contaminated sites. Overall, N,N-Dimethyldodecylamine N-oxide serves as a crucial tool in scientific research, facilitating the study of membrane proteins, protein extraction, and environmental remediation processes.


N,N-Dimethyldodecylamine N-oxide (CAS 1643-20-5) References

  1. Effect of detergent concentration on the thermal stability of a membrane protein: The case study of bacterial reaction center solubilized by N,N-dimethyldodecylamine-N-oxide.  |  Palazzo, G., et al. 2010. Biochim Biophys Acta. 1804: 137-46. PMID: 19786126
  2. Stimuli responsive polymorphism of C12NO/DOPE/DNA complexes: Effect of pH, temperature and composition.  |  Hubčík, L., et al. 2015. Biochim Biophys Acta. 1848: 1127-38. PMID: 25660321
  3. The impact of N,N-dimethyldodecylamine N-oxide (DDAO) concentration on the crystallisation of sodium dodecyl sulfate (SDS) systems and the resulting changes to crystal structure, shape and the kinetics of crystal growth.  |  Summerton, E., et al. 2018. J Colloid Interface Sci. 527: 260-266. PMID: 29800875
  4. Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-dimethyldodecylamine N-oxide aqueous systems performed at low temperatures.  |  Summerton, E., et al. 2019. J Colloid Interface Sci. 535: 1-7. PMID: 30268892
  5. The Amphoteric Surfactant N,N-Dimethyldodecylamine N-Oxide Unfolds β-Lactoglobulin above the Critical Micelle Concentration.  |  Thompson, KD., et al. 2022. Langmuir. 38: 4090-4101. PMID: 35325533
  6. Solution Structures of Anionic-Amphoteric Surfactant Mixtures near the Two-Phase Region at Fixed pH.  |  Tyagi, G., et al. 2022. Langmuir. 38: 7198-7207. PMID: 35658451
  7. Concentration Dependent Asymmetric Synergy in SDS-DDAO Mixed Surfactant Micelles.  |  Torquato, LMG., et al. 2024. Langmuir. 40: 7433-7443. PMID: 38532537
  8. Induction of tumours in rats by feeding nitrosatable amines together with sodium nitrite.  |  Lijinsky, W. 1984. Food Chem Toxicol. 22: 715-20. PMID: 6541624
  9. N-Nitroso-N-methyldodecylamine and N-nitroso-N-methyltetradecylamine in household dishwashing liquids.  |  Morrison, JB. and Hecht, SS. 1982. Food Chem Toxicol. 20: 583-6. PMID: 6890512

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N,N-Dimethyldodecylamine N-oxide, 5 g

sc-215498
5 g
$490.00