Date published: 2025-9-18

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N-Feruloyl Serotonin (CAS 68573-23-9)

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Alternate Names:
N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)-2-propenamide; N-Feruloylserotonin
Application:
N-Feruloyl Serotonin is N-Feruloyl Serotonin is a conjugated serotonin compound
CAS Number:
68573-23-9
Molecular Weight:
352.38
Molecular Formula:
C20H20N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Feruloyl Serotonin plays a functional role in cellular processes by interacting with molecular components. It influences cellular pathways through its mechanism of action, which involves modulating various signaling pathways and gene expression. N-Feruloyl Serotonin interacts with specific receptors and enzymes within cells, leading to the regulation of important cellular processes such as cell growth, differentiation, and apoptosis. Additionally, it′s antioxidant properties can help protect cells from oxidative damage. N-Feruloyl Serotonin modulates neurotransmitter levels and activity, impacting neuronal signaling and communication. Furthermore, N-Feruloyl Serotonin regulates inflammatory responses and immune function, suggesting a role in cellular defense mechanisms. Overall, the chemical′s interactions with cellular and molecular components contribute to its influence on various cellular processes and pathways.


N-Feruloyl Serotonin (CAS 68573-23-9) References

  1. Protective effect of serotonin derivatives on glucose-induced damage in PC12 rat pheochromocytoma cells.  |  Piga, R., et al. 2010. Br J Nutr. 103: 25-31. PMID: 19747415
  2. Synthesis and structure-activity relationships of phenylpropanoid amides of serotonin on tyrosinase inhibition.  |  Takahashi, T. and Miyazawa, M. 2011. Bioorg Med Chem Lett. 21: 1983-6. PMID: 21377874
  3. Serotonin derivatives as inhibitors of beta-secretase (BACE 1).  |  Takahashi, T. and Miyazawa, M. 2011. Pharmazie. 66: 301-5. PMID: 21612159
  4. Potent α-glucosidase inhibitors from safflower (Carthamus tinctorius L.) seed.  |  Takahashi, T. and Miyazawa, M. 2012. Phytother Res. 26: 722-6. PMID: 22021176
  5. Biotransformation of serotonin derivatives by the larvae of common cutworm (Spodoptera litura).  |  Takahashi, T. and Miyazawa, M. 2013. Nat Prod Res. 27: 592-6. PMID: 22889206
  6. Preparative Separation of N-Feruloyl Serotonin and N-(p-Coumaroyl) Serotonin from Safflower Seed Meal Using High-Speed Counter-Current Chromatography.  |  Zhang, Q., et al. 2015. J Chromatogr Sci. 53: 1341-5. PMID: 25744248
  7. Engineering of Escherichia coli for the synthesis of N-hydroxycinnamoyl tryptamine and serotonin.  |  Lee, SJ., et al. 2017. J Ind Microbiol Biotechnol. 44: 1551-1560. PMID: 28819877
  8. Protective Effect of Safflower Seed on Cisplatin-Induced Renal Damage in Mice via Oxidative Stress and Apoptosis-Mediated Pathways.  |  Park, CH., et al. 2018. Am J Chin Med. 46: 157-174. PMID: 29298512
  9. Safflower (Carthamus tinctorius L.) seed attenuates memory impairment induced by scopolamine in mice via regulation of cholinergic dysfunction and oxidative stress.  |  Kim, JH., et al. 2019. Food Funct. 10: 3650-3659. PMID: 31165850
  10. Genome-wide Dissection of Co-selected UV-B Responsive Pathways in the UV-B Adaptation of Qingke.  |  Zeng, X., et al. 2020. Mol Plant. 13: 112-127. PMID: 31669581
  11. Safflower Seed Extract Attenuates the Development of Osteoarthritis by Blocking NF-κB Signaling.  |  Han, SJ., et al. 2021. Pharmaceuticals (Basel). 14: PMID: 33809253
  12. Alterations in Gut Vitamin and Amino Acid Metabolism are Associated with Symptoms and Neurodevelopment in Children with Autism Spectrum Disorder.  |  Zhu, J., et al. 2022. J Autism Dev Disord. 52: 3116-3128. PMID: 34263410
  13. N-Feruloyl Serotonin Attenuates Neuronal Oxidative Stress and Apoptosis in Aβ25-35-Treated Human Neuroblastoma SH-SY5Y Cells.  |  He, M., et al. 2023. Molecules. 28: PMID: 36838597

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Feruloyl Serotonin, 25 mg

sc-498142
25 mg
$398.00