Molecular structure of mono-Methyl fumarate, CAS Number: 2756-87-8
mono-Methyl fumarate (CAS 2756-87-8)
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Alternate Names:
Fumaric acid monomethyl ester, Methyl hydrogen fumarate
Application:
mono-Methyl fumarate is a carbonyl compound for research purposes
CAS Number:
2756-87-8
Purity:
≥96%
Molecular Weight:
130.10
Molecular Formula:
C5H6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
mono-Methyl fumarate is a carbonyl compound for research purposes. mono-Methyl fumarate emerges as a significant metabolite derived from dimethyl fumarate (DMF), working as a mitochondrial membrane potential inhibition. This compound′s dynamic attributes extend to its potency as a nicotinic acid receptor agonist. It also has shown to selectively stimulate of T helper 2 cytokine response. Mono-Methyl fumarate demonstrates a broad-spectrum antibacterial effect, coupled with potent antioxidant capabilities.
mono-Methyl fumarate (CAS 2756-87-8) References
- Regulation of dimethyl-fumarate toxicity by proteasome inhibitors. | Booth, L., et al. 2014. Cancer Biol Ther. 15: 1646-57. PMID: 25482938
- Ruxolitinib synergizes with DMF to kill via BIM+BAD-induced mitochondrial dysfunction and via reduced SOD2/TRX expression and ROS. | Tavallai, M., et al. 2016. Oncotarget. 7: 17290-300. PMID: 26981780
- Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation. | Liu, X., et al. 2016. Biochem Pharmacol. 112: 37-49. PMID: 27184504
- Development and validation of a stability-indicating RP-HPLC method for the identification, determination of related substances and assay of dimethyl fumarate in drug substance. | Kommareddy, S., et al. 2021. Ann Pharm Fr. 79: 179-193. PMID: 33091397
- Dimethyl Fumarate Can Enhance the Potential Therapeutic Effects of Epidermal Neural Crest Stem Cells in COVID-19 Patients. | Safari, A., et al. 2021. Stem Cell Rev Rep. 17: 300-301. PMID: 33415541
- Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters. | Parker, SJ., et al. 2021. Nat Commun. 12: 4905. PMID: 34385458
- Mitochondrial Ultrastructure and Activity Are Differentially Regulated by Glycolysis-, Krebs Cycle-, and Microbiota-Derived Metabolites in Monocytes. | Pérez-Hernández, CA., et al. 2022. Biology (Basel). 11: PMID: 36009759
- Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells. | Vanhoutte, R., et al. 2023. Chem Sci. 14: 1666-1672. PMID: 36819852
- Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors. | Shungube, M., et al. 2023. RSC Adv. 13: 18991-19001. PMID: 37362332
Inhibitor of:
IRG1, PDH-E1β, and SDHB.Activator of:
β1-Adaptin, HM74A, and SLC25A36.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
mono-Methyl fumarate, 1 g | sc-235887 | 1 g | $27.00 | |||
mono-Methyl fumarate, 100 g | sc-235887A | 100 g | $67.00 | |||
mono-Methyl fumarate, 500 g | sc-235887B | 500 g | $204.00 | |||
mono-Methyl fumarate, 1 kg | sc-235887C | 1 kg | $341.00 |