Methyl 2-hydroxyethyl cellulose (CAS 9032-42-2)

Methyl 2-hydroxyethyl cellulose (MHEC) is a chemically modified derivative of cellulose, one of the most abundant organic materials on Earth. This modification introduces methyl and hydroxyethyl groups into the cellulose backbone, which significantly alters its properties. MHEC is highly soluble in water and some organic solvents, unlike the parent cellulose, making it an incredibly versatile polymer in various scientific and industrial applications. In research, MHEC is primarily utilized for its excellent film-forming, thickening, and stabilizing properties. It serves as an ideal medium in biofilms and as a viscosity modifier in aqueous solutions, which is crucial for controlling the release of substances in pharmaceutical formulations. MHEC′s role in drug delivery systems, particularly in hydrogel formulations, is of significant interest. These hydrogels can provide a controlled release matrix for active pharmaceutical ingredients, enhancing the efficacy and safety of drugs by regulating their release profiles. Furthermore, MHEC is employed in tissue engineering as a scaffold material due to its biocompatibility and structural similarity to the extracellular matrix of many tissues. It supports cell adhesion and proliferation, which are essential for tissue regeneration. Researchers also explore MHEC in 3D bioprinting applications, where it is used to structure complex tissue constructs.