Date published: 2025-10-18

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m-Xylene (CAS 108-38-3)

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Alternate Names:
1,3-Dimethylbenzene
Application:
m-Xylene is an organic solvent commonly used in histology
CAS Number:
108-38-3
Molecular Weight:
106.17
Molecular Formula:
C8H10
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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m-Xylene, formally known as meta-xylene, is an aromatic hydrocarbon with the chemical formula C8H10. It is one of the three isomeric dimethylbenzenes, distinguished by its two methyl groups attached at the meta positions (1,3) on the benzene ring. This structural configuration confers specific properties to m-xylene, such as its boiling point, solubility, and reactivity, which are distinct from those of its ortho and para isomers. As a clear, colorless liquid, m-Xylene is primarily used in the chemical industry as a solvent and as a precursor in the synthesis of isophthalic acid, an important compound used in the production of high-performance polymers and resins. In research, m-xylene′s non-polar nature and moderate evaporation rate make it a valuable solvent for the purification and processing of organic compounds, particularly in settings where the separation of mixtures via techniques like chromatography is required. The compound′s ability to dissolve a wide range of chemicals without interfering with their chemical properties is crucial for analytical and preparative applications in laboratories. Additionally, m-xylene is often used in the study of hydrocarbon structures and behaviors, providing insights into the interactions and stability of methyl-substituted benzene derivatives under various conditions. This research has implications for understanding and innovating in the fields of materials science, environmental chemistry, and industrial solvent applications, reflecting the compound′s versatile role beyond simple industrial usage.


m-Xylene (CAS 108-38-3) References

  1. Degradation of m-xylene solution using ultrasonic irradiation.  |  Xie, W., et al. 2011. Ultrason Sonochem. 18: 1077-81. PMID: 21489847
  2. Nonionic surfactant enhanced biodegradation of m-xylene by mixed bacteria and its application in biotrickling filter.  |  Wang, L., et al. 2018. J Air Waste Manag Assoc. 68: 1065-1076. PMID: 29672237
  3. [Immuno- and enzymehistochemical studies of methacrylate-embedded biopsy material, especially iliac crest biopsies].  |  Wolf, E., et al. 1988. Acta Histochem Suppl. 35: 179-88. PMID: 3138712
  4. Efficient Separation of Xylene Isomers by a Pillar-Layer Metal-Organic Framework.  |  Yang, L., et al. 2021. ACS Appl Mater Interfaces. 13: 41600-41608. PMID: 34455785
  5. Highly efficient degradation of hydrogen sulfide, styrene, and m-xylene in a bio-trickling filter.  |  Yao, X., et al. 2022. Sci Total Environ. 808: 152130. PMID: 34863757
  6. Interpenetrated metal-organic frameworks with enhanced photoluminescence for selective recognition of m-xylene from xylene isomers.  |  Zhang, X., et al. 2022. Dalton Trans. 51: 4790-4797. PMID: 35253813
  7. Separation of p-xylene and m-xylene by simulated moving bed chromatography with MIL-53(Fe) as stationary phase.  |  Peng, B. and Wang, S. 2022. J Chromatogr A. 1673: 463091. PMID: 35525192
  8. Staining method for whole-body autoradiography.  |  Watanabe, M., et al. 1975. Stain Technol. 50: 239-43. PMID: 52917
  9. A new organic solvent for use in the clearing of tissues. I. Soft tissue histology.  |  Wishe, HI., et al. 1980. Anat Rec. 197: 283-8. PMID: 6159808
  10. m-xylene toxicokinetics in phenobarbital-treated rats: comparison among inhalation exposure, oral administration, and intraperitoneal administration.  |  Kaneko, T., et al. 1995. Toxicol Appl Pharmacol. 131: 13-20. PMID: 7878667

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

m-Xylene, 0.5 L

sc-250273
0.5 L
$133.00