Molecular structure of Lasalocid sodium, CAS Number: 25999-20-6
Lasalocid sodium (CAS 25999-20-6)
See product citations (3)
Alternate Names:
Lasalocid sodium also known as Avatec; Bovatec; Lasalocid A
Application:
Lasalocid sodium is a polyether ionophore with potent antibacterial activity and is able to transport larger organic cations, e.g. protonated dopamine
CAS Number:
25999-20-6
Purity:
≥95%
Molecular Weight:
612.77
Molecular Formula:
C34H53O8•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Lasalocid sodium is a polyether ionophore with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid sodium is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase (including lipid bilayer membranes). Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine.
Lasalocid sodium (CAS 25999-20-6) References
- Determination of lasalocid residues in the tissues of broiler chickens by liquid chromatography-tandem mass spectrometry. | Tkáčiková, S., et al. 2012. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 29: 761-9. PMID: 22369356
- The protective effect of silybin against lasalocid cytotoxic exposure on chicken and rat cell lines. | Radko, L., et al. 2013. Biomed Res Int. 2013: 783519. PMID: 23509777
- Toxicity of the ionophore antibiotic lasalocid to soil-dwelling invertebrates: avoidance tests in comparison to classic sublethal tests. | Žižek, S. and Zidar, P. 2013. Chemosphere. 92: 570-5. PMID: 23635534
- Cytoprotective effect of silybin against lasalocid-induced toxicity in HepG2 cells. | Radko, L., et al. 2013. Pol J Vet Sci. 16: 275-82. PMID: 23971195
- Spectroscopic, crystallographic and theoretical studies of lasalocid complex with ammonia and benzylamine. | Huczyński, A., et al. 2014. Spectrochim Acta A Mol Biomol Spectrosc. 125: 297-307. PMID: 24562161
- Safety evaluation of lasalocid use in Chinese ring-necked pheasants (Phasianus colchicus). | Dzikamunhenga, RS., et al. 2013. Avian Dis. 57: 188-91. PMID: 24689172
- Administration of lasalocid-NA is preventive against cryptosporidiosis of newborn calves. | Murakoshi, F., et al. 2014. Vet Rec. 175: 353. PMID: 25155027
- Effect of distillers feedstuffs and lasalocid on Campylobacter carriage in feedlot cattle. | Anderson, RC., et al. 2014. J Food Prot. 77: 1968-75. PMID: 25364932
- Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. | Wong, FT., et al. 2015. J Am Chem Soc. 137: 86-9. PMID: 25535803
- Degradation and dissipation of the veterinary ionophore lasalocid in manure and soil. | Žižek, S., et al. 2015. Chemosphere. 138: 947-51. PMID: 25556006
- Development of intramammary delivery systems containing lasalocid for the treatment of bovine mastitis: impact of solubility improvement on safety, efficacy, and milk distribution in dairy cattle. | Wang, W., et al. 2015. Drug Des Devel Ther. 9: 631-42. PMID: 25653501
- Analysis of lasalocid residues in grease and fat using liquid chromatography-mass spectrometry. | Clark, SB., et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 1243-8. PMID: 26054429
- Spectroscopic studies of the equilibrium between complexes of lasalocid acid with propargylamine and metal cations. | Rutkowski, J., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 150: 704-11. PMID: 26093967
- A meta-analysis of lasalocid effects on rumen measures, beef and dairy performance, and carcass traits in cattle. | Golder, HM. and Lean, IJ. 2016. J Anim Sci. 94: 306-26. PMID: 26812337
- The Isolation of Three New Crystalline Antibiotics from Streptomyces | Julius Berger, et al. 1951. Journal of the American Chemical Society. 73: 5295–5298.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lasalocid sodium, 5 mg | sc-362029 | 5 mg | $160.00 | |||
Lasalocid sodium, 5 mg | sc-362029-CW | 5 mg | $185.00 | |||
Lasalocid sodium, 25 mg | sc-362029A | 25 mg | $550.00 |