Molecular structure of L-Ergothioneine, CAS Number: 497-30-3
L-Ergothioneine (CAS 497-30-3)
See product citations (6)
Alternate Names:
Ergothionine;L-(+)-Ergothioneine;Erythrothioneine
Application:
L-Ergothioneine is an antioxidant and free radical scavenger
CAS Number:
497-30-3
Purity:
≥95%
Molecular Weight:
229.30
Molecular Formula:
C9H15N3O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
L-Ergothioneine is a naturally occurring amino acid and is a significant subject of interest in various research applications in relation to its antioxidant properties. Studies frequently explore its role in oxidative stress and its ability to scavenge free radicals, which has implications for understanding cellular protection mechanisms. In agricultural research, L-Ergothioneine is examined for its presence in crops and its potential to enhance the nutritional value of food. Environmental science research investigates L-Ergothioneine′s distribution in different ecosystems and its bioaccumulation in organisms. Additionally, L-Ergothioneine is utilized in materials science to understand its stability and reactivity under various conditions, which can inform the design of new compounds with similar characteristics.
L-Ergothioneine (CAS 497-30-3) References
- Protection against oxidative damage and cell death by the natural antioxidant ergothioneine. | Aruoma, OI., et al. 1999. Food Chem Toxicol. 37: 1043-53. PMID: 10566875
- L-Ergothioneine scavenges superoxide and singlet oxygen and suppresses TNF-alpha and MMP-1 expression in UV-irradiated human dermal fibroblasts. | Obayashi, K., et al. 2005. J Cosmet Sci. 56: 17-27. PMID: 15744438
- A comparison of the relative antioxidant potency of L-ergothioneine and idebenone. | Dong, KK., et al. 2007. J Cosmet Dermatol. 6: 183-8. PMID: 17760697
- A Safety Evaluation of a Nature-Identical l-Ergothioneine in Sprague Dawley Rats. | Marone, PA., et al. 2016. Int J Toxicol. 35: 568-83. PMID: 27306320
- Anti-oxidative Amino Acid L-ergothioneine Modulates the Tumor Microenvironment to Facilitate Adjuvant Vaccine Immunotherapy. | Yoshida, S., et al. 2019. Front Immunol. 10: 671. PMID: 31019508
- Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of pre-eclampsia. | Morillon, AC., et al. 2020. PLoS One. 15: e0230977. PMID: 32231385
- Statement on the safety of synthetic l-ergothioneine as a novel food - supplementary dietary exposure and safety assessment for infants and young children, pregnant and breastfeeding women. | , ., et al. 2017. EFSA J. 15: e05060. PMID: 32625352
- L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway. | Dare, A., et al. 2021. Biomed Pharmacother. 141: 111921. PMID: 34346315
- Cardioprotective Effects and in-silico Antioxidant Mechanism of L-Ergothioneine in Experimental Type-2 Diabetic Rats. | Dare, A., et al. 2022. Cardiovasc Hematol Agents Med Chem. 20: 133-147. PMID: 34370646
- S-Methyl-L-Ergothioneine to L-Ergothioneine Ratio in Urine Is a Marker of Cystine Lithiasis in a Cystinuria Mouse Model. | López de Heredia, M., et al. 2021. Antioxidants (Basel). 10: PMID: 34573056
- L-ergothioneine and metformin alleviates liver injury in experimental type-2 diabetic rats via reduction of oxidative stress, inflammation, and hypertriglyceridemia. | Dare, A., et al. 2021. Can J Physiol Pharmacol. 99: 1137-1147. PMID: 34582252
- Matching chemical properties to molecular biological activities opens a new perspective on l-ergothioneine. | Yadan, JC. 2022. FEBS Lett. 596: 1299-1312. PMID: 34928499
- Efficient Synthesis of Food-Derived Antioxidant l-Ergothioneine by Engineered Corynebacterium glutamicum. | Kim, M., et al. 2022. J Agric Food Chem. 70: 1516-1524. PMID: 35088592
- l-Ergothioneine Exhibits Protective Effects against Dextran Sulfate Sodium-Induced Colitis in Mice. | Gao, Y., et al. 2022. ACS Omega. 7: 21554-21565. PMID: 35785312
- Determination of L-Ergothioneine in Cosmetics Based on Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry. | Liu, L., et al. 2022. Int J Anal Chem. 2022: 4372295. PMID: 36204714
Activator of:
β-Mercaptoethanol, γN-crystallin, and MsrA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Ergothioneine, 10 mg | sc-200814 | 10 mg | $112.00 | |||
L-Ergothioneine, 50 mg | sc-200814A | 50 mg | $449.00 | |||
L-Ergothioneine, 500 mg | sc-200814B | 500 mg | $714.00 |