Molecular structure of Isostearic acid, CAS Number: 2724-58-5
Isostearic acid (CAS 2724-58-5)
Alternate Names:
16-Methylheptadecanoic acid
Application:
Isostearic acid is a lipid used in the synthesis of biosurfactants
CAS Number:
2724-58-5
Purity:
≥97%
Molecular Weight:
284.48
Molecular Formula:
C18H36O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Isostearic acid is a saturated fatty acid found in a variety of animal and plant species. It is a component of many cell membranes and is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles. Additionally, it can modulate the activity of certain enzymes, including lipoxygenase, cyclooxygenase, and cytochrome P450, as well as inhibit the activity of certain transcription factors, such as NF-κB and AP-1. Moreover, Isostearic acid inhibits the growth of cancer cells. It has also been found to have anti-inflammatory and antioxidant properties.
Isostearic acid (CAS 2724-58-5) References
- Development of a topically active imiquimod formulation. | Chollet, JL., et al. 1999. Pharm Dev Technol. 4: 35-43. PMID: 10027211
- The branched-chain fatty acids of mutton fat. 3. The isolation of 16-methylheptadecanoic acid (isostearic acid). | COOKE, NJ., et al. 1956. Biochem J. 64: 214-6. PMID: 13363830
- Synthesis and steric stabilization of silver nanoparticles in neat carbon dioxide solvent using fluorine-free compounds. | Anand, M., et al. 2006. J Phys Chem B. 110: 14693-701. PMID: 16869575
- Methyl-branched poly(hydroxyalkanoate) biosynthesis from 13-methyltetradecanoic acid and mixed isostearic acid isomer substrates. | Ashby, RD., et al. 2009. Appl Microbiol Biotechnol. 85: 359-70. PMID: 19644690
- Facile synthesis of silver nanoparticles in CO2-expanded liquids from silver isostearate precursor. | Hsieh, HT., et al. 2010. Langmuir. 26: 10031-5. PMID: 20297774
- Aldara activates TLR7-independent immune defence. | Walter, A., et al. 2013. Nat Commun. 4: 1560. PMID: 23463003
- TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis. | Flutter, B. and Nestle, FO. 2013. Eur J Immunol. 43: 3138-46. PMID: 24254490
- The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers. | Kubota, K., et al. 2016. Eur J Pharm Sci. 86: 75-83. PMID: 26965004
- Microemulsions based on TPGS and isostearic acid for imiquimod formulation and skin delivery. | Pescina, S., et al. 2018. Eur J Pharm Sci. 125: 223-231. PMID: 30316975
- Intradermal Delivery of an Immunomodulator for Basal Cell Carcinoma; Expanding the Mechanistic Insight into Solid Microneedle-Enhanced Delivery of Hydrophobic Molecules. | Sabri, A., et al. 2020. Mol Pharm. 17: 2925-2937. PMID: 32510228
- Low Temperature Affects Fatty Acids Profiling and Key Synthesis Genes Expression Patterns in Zanthoxylum bungeanum Maxim. | Tian, J., et al. 2022. Int J Mol Sci. 23: PMID: 35216434
- Viscosity of Nanoconfined Branched-Chain Fatty Acids Studied by Resonance Shear Measurements. | Iizuka, M., et al. 2022. Langmuir. 38: 12944-12950. PMID: 36240007
- Selective extraction equilibria of Sc(III), Y(III), Fe(III) and Al(III) from acidic media with toluene mixture of deep eutectic solvent (DES) composed of TOPO and isostearic acid. | Ushizaki, S., et al. 2023. Anal Sci. 39: 473-481. PMID: 36807888
- Isostearic acid is an active component of imiquimod formulations used to induce psoriaform disease models. | Straß, S., et al. 2023. Inflammopharmacology. 31: 799-812. PMID: 36943539
- Curcumin in a model skin lotion formulation. | Suhaimi, H., et al. 1995. J Pharm Sci. 84: 376-80. PMID: 7616381
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Isostearic acid, 25 mg | sc-215200 | 25 mg | $265.00 |