Date published: 2025-11-29

1-800-457-3801

SCBT Portrait Logo
Seach Input

Imidazole (CAS 288-32-4)

5.0(2)
Write a reviewAsk a question

See product citations (2)

Alternate Names:
1,3-Diaza-2,4-cyclopentadiene
Application:
Imidazole is a buffer useful in the pH range of 6.2-7.8
CAS Number:
288-32-4
Purity:
≥99%
Molecular Weight:
68.08
Molecular Formula:
C3H4N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Imidazole is useful as a buffer in the pH range of 6.2-7.8. One of the applications of imidazole is in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). Imidazole is used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chromatography column. An excess of imidazole is passed through the column, which displaces the His-tag from nickel co-ordination, freeing the His-tagged proteins. Imidazole is part of the theophylline molecule, found in tea leaves and coffee beans, which stimulates the central nervous system.


Imidazole (CAS 288-32-4) References

  1. Imidazole catalyzes chlorination by unreactive primary chloramines.  |  Roemeling, MD., et al. 2015. Free Radic Biol Med. 82: 167-78. PMID: 25660996
  2. Current and Future Prospective of a Versatile Moiety: Imidazole.  |  Rani, N., et al. 2020. Curr Drug Targets. 21: 1130-1155. PMID: 32472996
  3. In situ photoconductivity measurements of imidazole in optical fiber break-junctions.  |  Zhao, Z., et al. 2021. Nanoscale Horiz. 6: 386-392. PMID: 33949578
  4. Effect of Imidazole as Corrosion Inhibitor on Carbon Steel Weldment in District Heating Water.  |  Ko, SJ., et al. 2021. Materials (Basel). 14: PMID: 34442932
  5. Imidazole Compounds: Synthesis, Characterization and Application in Optical Analysis.  |  Wang, J., et al. 2022. Crit Rev Anal Chem. 1-26. PMID: 35001757
  6. Association with Imidazole in the Cooperative Order-Disorder Transition in Aqueous Solution of Schizophyllan.  |  Yoshiba, K., et al. 2022. Langmuir. 38: 1748-1756. PMID: 35089712
  7. Galactose-imidazole mediated dual-targeting fluorescent probe for detecting Fe3+ in the lysosomes of hepatocytes: Design, synthesis and evaluation.  |  Wang, Y., et al. 2022. Biosens Bioelectron. 204: 114083. PMID: 35176648
  8. Anticancer effects of imidazole nucleus in hepatocellular carcinoma cell lines via the inhibition of AKT and ERK1/2 signaling pathways.  |  Kahraman, E. and Göker, E. 2022. Mol Biol Rep. 49: 4377-4388. PMID: 35226260
  9. Cross-Linking of Polypropylene with Thiophene and Imidazole.  |  Muljana, H., et al. 2022. Polymers (Basel). 14: PMID: 35683871
  10. Design, Synthesis, and Application of Chiral Bicyclic Imidazole Catalysts.  |  Wang, M., et al. 2022. Acc Chem Res. 55: 2708-2727. PMID: 36043467
  11. Imidazole and Derivatives Drugs Synthesis: A Review.  |  Rani, N., et al. 2022. Curr Org Synth.. PMID: 36411575
  12. An Imidazole-Based Triangular Macrocycle for Visual Detection of Formaldehyde.  |  Yu, MY., et al. 2022. Inorg Chem. 61: 20200-20205. PMID: 36472479
  13. Mechanism of imidazole inhibition of a GH1 β-glucosidase.  |  Chagas, RS., et al. 2023. FEBS Open Bio.. PMID: 36906930

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Imidazole, 25 g

sc-204776
25 g
$26.00
US: Only available in the US

Imidazole, 100 g

sc-204776A
100 g
$55.00
US: Only available in the US

Imidazole, 1 kg

sc-204776B
1 kg
$82.00
US: Only available in the US

Imidazole, 5 kg

sc-204776C
5 kg
$336.00
US: Only available in the US