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(Hydroxypropyl)methyl cellulose (CAS 9004-65-3)

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Alternate Names:
Methocel; HPMC
Application:
(Hydroxypropyl)methyl cellulose is a thickener for aqueous and non-aqueous systems
CAS Number:
9004-65-3
Molecular Weight:
1261.44
Molecular Formula:
C56H108O30
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(Hydroxypropyl)methyl cellulose is a thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid. Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface actuce and enzyme resistant. Solutions are pseudoplastic.


(Hydroxypropyl)methyl cellulose (CAS 9004-65-3) References

  1. Hydroxypropyl methyl cellulose grafted with polyacrylamide: application in controlled release of 5-amino salicylic acid.  |  Das, R. and Pal, S. 2013. Colloids Surf B Biointerfaces. 110: 236-41. PMID: 23732799
  2. Safety and efficacy of hydroxypropyl methyl cellulose for all animal species.  |  , ., et al. 2020. EFSA J. 18: e06214. PMID: 32760470
  3. Structural Study of (Hydroxypropyl)Methyl Cellulose Microemulsion-Based Gels Used for Biocompatible Encapsulations.  |  Vassiliadi, E., et al. 2020. Nanomaterials (Basel). 10: PMID: 33167302
  4. Embedding Silver Nanowires into a Hydroxypropyl Methyl Cellulose Film for Flexible Electrochromic Devices with High Electromechanical Stability.  |  Li, D., et al. 2021. ACS Appl Mater Interfaces. 13: 1735-1742. PMID: 33356085
  5. Controlled Release of Curcumin from HPMC (Hydroxypropyl Methyl Cellulose) Co-Spray-Dried Materials.  |  Zheng, J., et al. 2021. Bioinorg Chem Appl. 2021: 7625585. PMID: 34220997
  6. Ethyl Cellulose and Hydroxypropyl Methyl Cellulose Blended Methotrexate-Loaded Transdermal Patches: In Vitro and Ex Vivo.  |  Latif, MS., et al. 2021. Polymers (Basel). 13: PMID: 34685214
  7. Preparation and fertilizer retention/anti-leakage performances of superabsorbent composite based on hydroxypropyl methyl cellulose.  |  Ye, X., et al. 2021. Carbohydr Polym. 274: 118636. PMID: 34702459
  8. Optimization of Spray-Drying Process Parameters to Study Anti-Sticking Effect of Hydroxypropyl Methyl Cellulose-VLV on Corni fructus Extracts.  |  Cheng, H., et al. 2022. AAPS PharmSciTech. 23: 58. PMID: 35059874
  9. Development of xanthan gum/hydroxypropyl methyl cellulose composite films incorporating tea polyphenol and its application on fresh-cut green bell peppers preservation.  |  Chen, J., et al. 2022. Int J Biol Macromol. 211: 198-206. PMID: 35568150
  10. Environmental-Friendly Adsorbent Composite Based on Hydroxyapatite/Hydroxypropyl Methyl-Cellulose for Removal of Cationic Dyes from an Aqueous Solution.  |  Akartasse, N., et al. 2022. Polymers (Basel). 14: PMID: 35683819
  11. Ionic conductive hydroxypropyl methyl cellulose reinforced hydrogels with extreme stretchability, self-adhesion and anti-freezing ability for highly sensitive skin-like sensors.  |  Qin, Z., et al. 2022. Int J Biol Macromol. 220: 90-96. PMID: 35970366
  12. Semisolid Wet Sol-Gel Silica/Hydroxypropyl Methyl Cellulose Formulation for Slow Release of Serpin B3 Promotes Wound Healing In Vivo.  |  Albiero, M., et al. 2022. Pharmaceutics. 14: PMID: 36145692
  13. Hydroxypropyl methyl cellulose reinforced conducting polymer hydrogels with ultra-stretchability and low hysteresis as highly sensitive strain sensors for wearable health monitoring.  |  Xu, L., et al. 2023. Int J Biol Macromol. 236: 123956. PMID: 36898462

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(Hydroxypropyl)methyl cellulose, 50 g

sc-279197
50 g
$65.00

(Hydroxypropyl)methyl cellulose, 250 g

sc-279197A
250 g
$215.00

(Hydroxypropyl)methyl cellulose, 1 kg

sc-279197B
1 kg
$500.00

what is the refractive Index and dielectric current of CAS 9004-65-3

Asked by: Hammza1999
Thank you for your question. Unfortunately, we do not have this information.
Answered by: Technical Support
Date published: 2019-07-25

What is the viscosity range of this HPMC?

Asked by: hporter
Thank you for your question. 28-30% methoxyl, 7-12% hydroxypropyl, viscosity (2% in H20, 20°C), 40-60 mPa.s.
Answered by: Technical Support
Date published: 2021-09-22
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Rated 5 out of 5 by from GoldGold, GT. et al. (PubMed 26428151) developed crosslinked (Hydroxypropyl)methyl cellulose hydrogels for soft tissue augmentation using an ammonium persulfate-ascorbic acid redox system. -SCBT Publication Review
Date published: 2015-06-15
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(Hydroxypropyl)methyl cellulose is rated 5.0 out of 5 by 1.
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