Date published: 2025-11-2

1-800-457-3801

SCBT Portrait Logo
Seach Input

Hydroxyethyl starch (CAS 9005-27-0)

5.0(1)
Write a reviewAsk a question

Alternate Names:
HES
Application:
Hydroxyethyl starch is a substituted starch
CAS Number:
9005-27-0
Purity:
≥99%
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Hydroxyethyl starch (HES) is a synthetic, highly branched amylopectin derivative, extensively utilized in various research applications, particularly for its role in modulating fluid dynamics and membrane permeability in experimental models. As a colloid, Hydroxyethyl starch has unique physicochemical properties that enable it to effectively influence osmotic pressure and volume expansion in experimental systems, making it an invaluable tool for studies focused on understanding the intricacies of fluid management and vascular integrity. Its mechanism of action is primarily through the enhancement of oncotic pressure, mimicking the physiological effects of natural colloids in the body′s fluid compartments. This property of Hydroxyethyl starch is for researchers aiming to dissect the fundamental processes governing fluid equilibrium and transport across cellular barriers. Moreover, the ability of Hydroxyethyl starch to modify the rheological properties of fluids it is added to has led to its widespread application in experiments designed to explore hemodynamics and the viscoelastic properties of biological fluids. As such, Hydroxyethyl starch occupies a pivotal role in the arsenal of research methodologies aimed at elucidating fundamental biological and physiological mechanisms.


Hydroxyethyl starch (CAS 9005-27-0) References

  1. Histological and immunohistochemical investigations of hydroxyethyl-starch deposits in rat tissues.  |  Parth, E., et al. 1992. Eur Surg Res. 24: 13-21. PMID: 1375158
  2. Mechanism of the effect of hydroxyethyl starch on reducing pulmonary capillary permeability in a rat model of sepsis.  |  Lv, R., et al. 2005. Ann Clin Lab Sci. 35: 174-83. PMID: 15943182
  3. Evaluation of UW solution in a rat kidney preservation model. I. Effect of hydroxyethyl starch and electrolyte composition.  |  Biguzas, M., et al. 1990. Transplantation. 49: 872-5. PMID: 1692429
  4. Hydroxyethyl starch normalizes platelet and leukocyte adhesion within pulmonary microcirculation during LPS-induced endotoxemia.  |  Küpper, S., et al. 2007. Shock. 28: 300-8. PMID: 17545948
  5. A method for detection and quantification of hydroxyethyl starch in plasma.  |  Otto, GP., et al. 2012. Crit Care. 16: 426. PMID: 22574909
  6. Effect of different freezing rates during cryopreservation of rat mesenchymal stem cells using combinations of hydroxyethyl starch and dimethylsulfoxide.  |  Naaldijk, Y., et al. 2012. BMC Biotechnol. 12: 49. PMID: 22889198
  7. Role of hydroxyethyl starch in ischemia-reperfusion injury in rat intestinal transplantation.  |  Li, XL., et al. 2013. Transplant Proc. 45: 2491-6. PMID: 23953568
  8. A systematic evaluation of hydroxyethyl starch as a potential nanocarrier for parenteral drug delivery.  |  Narayanan, D., et al. 2015. Int J Biol Macromol. 74: 575-84. PMID: 25572720
  9. Polymerized human placenta hemoglobin improves resuscitative efficacy of hydroxyethyl starch in a rat model of hemorrhagic shock.  |  Li, Y., et al. 2015. Artif Cells Nanomed Biotechnol. 43: 174-9. PMID: 25812000
  10. Extracorporeal rewarming from experimental hypothermia: Effects of hydroxyethyl starch versus saline priming on fluid balance and blood flow distribution.  |  Schanche, T., et al. 2019. Exp Physiol. 104: 1353-1362. PMID: 31219201
  11. Validation of the relationship between coagulopathy and localization of hydroxyethyl starch on the vascular endothelium in a rat hemodilution model.  |  Azumaguchi, R., et al. 2021. Sci Rep. 11: 10694. PMID: 34021192
  12. Author Correction: Validation of the relationship between coagulopathy and localization of hydroxyethyl starch on the vascular endothelium in a rat hemodilution model.  |  Azumaguchi, R., et al. 2021. Sci Rep. 11: 17697. PMID: 34465869
  13. Hydroxyethyl Starch Improves the Prognosis of Rats with Traumatic Shock via Activation of the ERK Signaling Pathway in Lymphocytes.  |  Liu, Y., et al. 2022. Comput Math Methods Med. 2022: 5262189. PMID: 35178114
  14. S/O/W microparticles prepared with hydroxyethyl starch-based emulsifier showed reduced macrophage affinity.  |  Li, Q., et al. 2022. Colloids Surf B Biointerfaces. 220: 112917. PMID: 36272284
  15. The effects of hydroxyethyl starch and gelatine on lung tissue and coagulation during the resuscitation of rats with traumatic haemorrhagic shock.  |  Saracoglu, A., et al. 2022. Anaesthesiol Intensive Ther. 54: 393-401. PMID: 36734450

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydroxyethyl starch, 250 g

sc-215159
250 g
$80.00

Hydroxyethyl starch, 1 kg

sc-215159A
1 kg
$223.00

Do you ship only to laboratories?

Asked by: Doctor Pepper
Thank you for your question. We ship to research labs and companies . We do not ship to residential locations.
Answered by: BlakeJ
Date published: 2023-12-29

hydroxyethyl starch 1kg 구매가능한지요?

Asked by: vinaka00
hydroxyethyl starch 1kg ;sc-215159A는 구매가능합니다. 구매하려면 우리 회사 한국에 있는 distributor에게 연락해 주십시오.아래는 연락처입니다.다른 문의사항은 언제든지 메일로 기술지원팀에게 보내주시기 바랍니다.we can provide 1kg of hydroxyethyl starch ,the catalog is sc-215159A. Below is the address of our distributor in Korea.Please contact Technical Service by phone, (800)-457-3801 option 2, email <asia@scbio.com>, or by live chat directly on our website, www.scbt.com if you have any further questions. Your local distributor(s): Essence Medical Inc. Korea Tel. 82-31-707-1544 FAX: 82-31-707-1999 Email: info@essencemedical.com Website: http://www.essencemedical.com Koram Biotech Corporation Korea Tel. 82 (2) 556-0311 FAX: 82 (2) 556-0828 Email: koram@korambiotech.com Website: http://www.korambiotech.com
Answered by: Technical Service 11
Date published: 2020-03-16

Is this HES available now?

Asked by: Yaburo
Thank you for your question. For accurate availability, shipping and pricing information regarding our chemical products, please contact Customer Service.
Answered by: Tech Service
Date published: 2019-11-15

We are looking for excipient grade hydroxymethy starch. your website does not give details about the quality of the product. Also please mention the molecular weight of the polymer.

Asked by: Mrityunjay
Thank you for your question. As stated on our website, this chemical is for research use only. Not suitable for diagnostic or therapeutic use.
Answered by: Technical Support
Date published: 2019-06-16

can we prepare 450000 molecular weight HES isotonic suspension from this power

Asked by: pradnya
Thank you for your question. The MW is 115000-145000 with MF (C6H10O5)m(C2H5O)n.
Answered by: Technical Support
Date published: 2019-06-16

What is the molecular weight of this product?

Asked by: two2igm05
Thank you for your question. The MW is 115000-145000 with MF (C6H10O5)m(C2H5O)n. Please contact Technical Service if you have further questions concerning this product.
Answered by: Tech Service 9
Date published: 2017-01-05
  • y_2025, m_10, d_14, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_6
  • loc_en_US, sid_215159, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 119ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from KnelsKnels. L. et al. (PubMed 25287368) reported that serum-free medium and Hydroxyethyl starch supports cell survival better than Minimal Essential Medium and dextran in organ-cultured mouse corneas. -SCBT Publication Review
Date published: 2015-02-22
  • y_2025, m_10, d_14, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_215159, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 16ms
  • REVIEWS, PRODUCT
Hydroxyethyl starch is rated 5.0 out of 5 by 1.
  • y_2025, m_10, d_14, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_215159, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 105ms
  • REVIEWS, PRODUCT