Molecular structure of Hydroxyectoine, CAS Number: 165542-15-4
Hydroxyectoine (CAS 165542-15-4)
Alternate Names:
THP(A); 5-hydroxyectoine
Application:
Hydroxyectoine is a compound used to stabilize enzymes and biological macromolecules
CAS Number:
165542-15-4
Purity:
≥95%
Molecular Weight:
158.16
Molecular Formula:
C6H10N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hydroxyectoine, also known as 5-Hydroxyectoine, a carboxamidine heterocycle, is synthesized through the condensation of 4-amino-L-allothreonine and acetic acid. It belongs to the class of 1,4,5,6-tetrahydropyrimidines and serves as a monocarboxylic acid and a secondary alcohol. This compound has demonstrated potential applications in protein stabilization, biomolecule protection against oxidative stress, biofuel production, and chelation of metals and other molecules.
Hydroxyectoine (CAS 165542-15-4) References
- High-yield cultivation of Marinococcus M52 for production and recovery of hydroxyectoine. | Schiraldi, C., et al. 2006. Res Microbiol. 157: 693-9. PMID: 16815686
- A specialized aspartokinase enhances the biosynthesis of the osmoprotectants ectoine and hydroxyectoine in Pseudomonas stutzeri A1501. | Stöveken, N., et al. 2011. J Bacteriol. 193: 4456-68. PMID: 21725014
- Glass-forming property of hydroxyectoine is the cause of its superior function as a desiccation protectant. | Tanne, C., et al. 2014. Front Microbiol. 5: 150. PMID: 24772110
- The hydroxyectoine gene cluster of the non-halophilic acidophile Acidiphilium cryptum. | Moritz, KD., et al. 2015. Extremophiles. 19: 87-99. PMID: 25142158
- Hydroxyectoine protects Mn-depleted photosystem II against photoinhibition acting as a source of electrons. | Yanykin, DV., et al. 2019. Photosynth Res. 141: 165-179. PMID: 30701483
- Effect of ectoine, hydroxyectoine and β-hydroxybutyrate on the temperature and pressure stability of phospholipid bilayer membranes of different complexity. | Herzog, M., et al. 2019. Colloids Surf B Biointerfaces. 178: 404-411. PMID: 30903979
- Exploring useful fermentation strategies for the production of hydroxyectoine with a halophilic strain, Halomonas salina BCRC 17875. | Chen, WC., et al. 2019. J Biosci Bioeng. 128: 332-336. PMID: 30935782
- Anhydrobiotic engineering for the endophyte bacterium Kosakonia radicincitans by osmoadaptation and providing exogenously hydroxyectoine. | Cruz Barrera, M., et al. 2019. World J Microbiol Biotechnol. 36: 6. PMID: 31832888
- Ectoine and Hydroxyectoine Stabilize Antibodies in Spray-Dried Formulations at Elevated Temperature and during a Freeze/Thaw Process. | Nayak, PK., et al. 2020. Mol Pharm. 17: 3291-3297. PMID: 32672979
- Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture. | Tsai, T., et al. 2020. Graefes Arch Clin Exp Ophthalmol. 258: 2185-2203. PMID: 32710140
- Microbial production of ectoine and hydroxyectoine as high-value chemicals. | Liu, M., et al. 2021. Microb Cell Fact. 20: 76. PMID: 33771157
- New insights into hydroxyectoine synthesis and its transcriptional regulation in the broad-salt growing halophilic bacterium Chromohalobacter salexigens. | Argandoña, M., et al. 2021. Microb Biotechnol. 14: 1472-1493. PMID: 33955667
- Metabolic engineering of Escherichia coli for efficient osmotic stress-free production of compatible solute hydroxyectoine. | Ma, Q., et al. 2022. Biotechnol Bioeng. 119: 89-101. PMID: 34612520
- High-efficiency production of 5-hydroxyectoine using metabolically engineered Corynebacterium glutamicum. | Jungmann, L., et al. 2022. Microb Cell Fact. 21: 274. PMID: 36578077
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydroxyectoine, 1 g | sc-215158 | 1 g | $48.00 | |||
Hydroxyectoine, 10 g | sc-215158A | 10 g | $285.00 |