Date published: 2025-11-18

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Hydroxyacetone (CAS 116-09-6)

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Alternate Names:
Acetol
Application:
Hydroxyacetone is used to study aerobic oxidation of glycerol and propanediol over metal oxide supported gold nanoparticles in methanol.
CAS Number:
116-09-6
Purity:
≥90%
Molecular Weight:
74.08
Molecular Formula:
C3H6O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hydroxyacetone was used to study aerobic oxidation of glycerol and propanediol over metal oxide supported gold nanoparticles in methanol. It is important for the manufacture of polyols, acrolein, dyes and skin tanning agents. It undergoes asymmetric reduction to yield (R)-1,2-propanediol in the presence of microbial cell catalyst. Hydroxyacetone (HA) is a naturally occurring chemical compound present in various plants and animals, including humans. This three-carbon molecule bears a hydroxyl group attached to one of its carbon atoms. It plays a pivotal role as an essential intermediate in numerous biochemical pathways, contributing to the production of energy, amino acids, and various other molecules. The scientific research applications of Hydroxyacetone are diverse and abundant. Its use spans multiple areas, from elucidating enzyme mechanisms to exploring the biochemistry of metabolic pathways. Additionally, Hydroxyacetone′s significance extends to the study of protein structure and function. Moreover, it has been employed in the synthesis of other compounds, such as amino acids, and has contributed to advancements in new material development. While the exact mechanism of action of Hydroxyacetone remains somewhat elusive, it is believed to function as a coenzyme, facilitating enzyme catalysis. Its involvement in synthesizing energy, amino acids, and other vital molecules is evident, alongside its role in the production and regulation of hormones like adrenaline and cortisol, as well as the metabolism of fatty acids. The versatile nature of Hydroxyacetone continues to intrigue researchers, holding promise for potential breakthroughs in various scientific domains.


Hydroxyacetone (CAS 116-09-6) References

  1. Vibrational analysis of hydroxyacetone.  |  Mohacek-Grosev, V. 2005. Spectrochim Acta A Mol Biomol Spectrosc. 61: 477-84. PMID: 15582815
  2. Biochemical origins of lactaldehyde and hydroxyacetone in Methanocaldococcus jannaschii.  |  White, RH. 2008. Biochemistry. 47: 5037-46. PMID: 18363381
  3. Measurement of atmospheric hydroxyacetone, glycolaldehyde, and formaldehyde.  |  Zhou, X., et al. 2009. Environ Sci Technol. 43: 2753-9. PMID: 19475945
  4. Conformation-changing aggregation in hydroxyacetone: a combined low-temperature FTIR, jet, and crystallographic study.  |  Sharma, A., et al. 2011. J Am Chem Soc. 133: 20194-207. PMID: 21961479
  5. Proton transfer reactions between nitric acid and acetone, hydroxyacetone, acetaldehyde and benzaldehyde in the solid phase.  |  Lasne, J., et al. 2012. Phys Chem Chem Phys. 14: 15715-21. PMID: 23090634
  6. Hydrogen-driven asymmetric reduction of hydroxyacetone to (R)-1,2-propanediol by Ralstonia eutropha transformant expressing alcohol dehydrogenase from Kluyveromyces lactis.  |  Oda, T., et al. 2013. Microb Cell Fact. 12: 2. PMID: 23305396
  7. Hydroxyacetone Production From C3 Criegee Intermediates.  |  Taatjes, CA., et al. 2017. J Phys Chem A. 121: 16-23. PMID: 28001404
  8. Hydroxyacetone: A Glycerol-Based Platform for Electrocatalytic Hydrogenation and Hydrodeoxygenation Processes.  |  Sauter, W., et al. 2017. ChemSusChem. 10: 3105-3110. PMID: 28643864
  9. The production of formaldehyde and hydroxyacetone in methacrolein photooxidation: New insights into mechanism and effects of water vapor.  |  Xing, Y., et al. 2018. J Environ Sci (China). 66: 1-11. PMID: 29628075
  10. Selective Conversion of Cellulose to Hydroxyacetone and 1-Hydroxy-2-Butanone with Sn-Ni Bimetallic Catalysts.  |  Wang, H., et al. 2019. ChemSusChem. 12: 2154-2160. PMID: 30767387
  11. Organocatalytic Asymmetric Aldol Reaction of Arylglyoxals and Hydroxyacetone: Enantioselective Synthesis of 2,3-Dihydroxy-1,4-diones.  |  Zhou, YH., et al. 2020. Molecules. 25: PMID: 32028657
  12. Temperature-Dependent Kinetic Study of the Reaction of Hydroxyl Radicals with Hydroxyacetone.  |  Bedjanian, Y. 2020. J Phys Chem A. 124: 2863-2870. PMID: 32172569
  13. Formation and photochemical investigation of brown carbon by hydroxyacetone reactions with glycine and ammonium sulfate.  |  Gao, Y. and Zhang, Y. 2018. RSC Adv. 8: 20719-20725. PMID: 35542337

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydroxyacetone, 5 g

sc-224018
5 g
$42.00

Hydroxyacetone, 100 g

sc-224018A
100 g
$47.00