Hydrazine sulfate is a useful agent for the N-deacylation of various molecules. In the N-deacylation of the ceramide moiety of glycosphingolipids, Hydrazine sulfate was an effective catalyst for the deacylation of the ceramide moiety. It has been used in a modified hydrazinolysis procedure in which the glycosaminoglycans were heated with a hydrazine solution resulting in rapid rates of N-deacetylation and minimal conversion of uronic acid residues to their hydrazide derivatives.
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