Date published: 2025-10-20

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Hexylene glycol (CAS 107-41-5)

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Alternate Names:
(±)-2-Methyl-2,4-pentanediol, MPD
CAS Number:
107-41-5
Molecular Weight:
118.17
Molecular Formula:
C6H14O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexylene glycol is characterized as a clear, colorless, and odorless liquid that finds extensive use in numerous industries, such as cosmetics and personal care products. It′s a category of glycol often utilized as a solvent, humectant, and an agent to control viscosity. Moreover, it acts as a reagent in the synthesis of diverse chemicals. With regard to scientific research applications, hexylene glycol serves as a solvent to extract an array of compounds from plant and animal tissues. It′s also employed as a reagent in the creation of various chemicals, including agrochemicals and fragrances. In the realm of cosmetics and personal care products, hexylene glycol functions as a preservative. It′s a humectant that aids in skin moisture retention and enhances skin texture and appearance. It operates by forming a barrier on the skin to impede moisture loss. Additionally, it helps to decrease the skin′s surface tension, thereby facilitating the penetration of other ingredients into the skin.


Hexylene glycol (CAS 107-41-5) References

  1. Pluronic F-127 gels as a vehicle for topical formulations of indomethacin and rheological behaviour of these formulations.  |  Shawesh, A., et al. 2002. Pharmazie. 57: 186-90. PMID: 11933848
  2. Influence of storage time and temperature on the stability of indomethacin Pluronic F-127 gels.  |  Shawesh, A., et al. 2002. Pharmazie. 57: 690-4. PMID: 12426950
  3. The OH-initiated oxidation of hexylene glycol and diacetone alcohol.  |  Magneron, I., et al. 2003. Environ Sci Technol. 37: 4170-81. PMID: 14524450
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  5. Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles.  |  Mitchison, TJ., et al. 2005. Mol Biol Cell. 16: 3064-76. PMID: 15788560
  6. Induction of cytokinesis is independent of precisely regulated microtubule dynamics.  |  Strickland, LI., et al. 2005. Mol Biol Cell. 16: 4485-94. PMID: 16014607
  7. Atomic force microscopy of native human metaphase chromosomes in a liquid.  |  Hoshi, O., et al. 2006. Arch Histol Cytol. 69: 73-8. PMID: 16609271
  8. Formulation of creams with betamethasone dipropionate: evaluation of chemical stability.  |  Băiţan, M., et al. 2010. Rev Med Chir Soc Med Nat Iasi. 114: 600-4. PMID: 20701012
  9. Controlling the bio-inspired synthesis of silica.  |  Garakani, TM., et al. 2017. J Colloid Interface Sci. 488: 322-334. PMID: 27838557
  10. Use of mobile phase additives for the elution of bispecific and monoclonal antibodies from phenyl based hydrophobic interaction chromatography resins.  |  Hall, T., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1096: 20-30. PMID: 30130673
  11. Investigations on Alkanediols as Alternative Preservatives in a Nonionic Hydrophilic Cream.  |  Sigg, M. and Daniels, R. 2020. Pharmaceutics. 12: PMID: 33233527
  12. Study of Thermodynamic and Acoustic Properties of Niacin in Aqueous Hexylene Glycol and Propylene Glycol at Different Temperatures.  |  Chakraborty, N., et al. 2020. ACS Omega. 5: 32357-32365. PMID: 33376872
  13. Methylprednisolone-induced anaphylaxis diagnosed by intradermal skin test: a case report.  |  Amano, H., et al. 2021. Allergy Asthma Clin Immunol. 17: 70. PMID: 34256829
  14. Correlating Hydration of Alkali-Activated Slag Modified by Organic Additives to the Evolution of Its Properties.  |  Bílek, V., et al. 2023. Materials (Basel). 16: PMID: 36903022

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexylene glycol, 500 ml

sc-250114
500 ml
$52.00

Hexylene glycol, 3 L

sc-250114A
3 L
$103.00