Date published: 2025-10-3

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Helicin (CAS 618-65-5)

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Alternate Names:
Salicylaldehyde β-D-glucoside
CAS Number:
618-65-5
Molecular Weight:
284.26
Molecular Formula:
C13H16O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Helicin, a glucoside derived from salicin, is an intriguing chemical compound extensively studied for its role in basic and applied plant sciences. As a natural compound, helicin undergoes enzymatic conversion back to salicylaldehyde, a process that has been pivotal in studies investigating plant defense mechanisms and metabolic pathways. This conversion is significant in understanding the biochemistry of plant phenolics and their ecological interactions, such as pest resistance and stress response mechanisms. In research, helicin′s properties are explored primarily in the context of plant biology, where it serves as a model compound for studying the hydrolysis of glycosides by specific enzymes, notably β-glucosidases. This aspect is crucial for advancing our understanding of glycosylation and its impact on plant biochemistry. Moreover, helicin has been utilized in studies related to phytoremediation, examining its role in the detoxification processes of plants, as it can modulate the levels of related salicyl compounds that influence plant health and growth under various environmental stresses. Through these research applications, helicin contributes significantly to our comprehension of plant metabolic processes and offers insights into the potential uses of natural compounds in enhancing agricultural productivity and environmental sustainability.


Helicin (CAS 618-65-5) References

  1. Characterization of an unusual cold-active beta-glucosidase belonging to family 3 of the glycoside hydrolases from the psychrophilic isolate Paenibacillus sp. strain C7.  |  Shipkowski, S. and Brenchley, JE. 2005. Appl Environ Microbiol. 71: 4225-32. PMID: 16085807
  2. Arabidopsis sucrose transporter AtSUC9. High-affinity transport activity, intragenic control of expression, and early flowering mutant phenotype.  |  Sivitz, AB., et al. 2007. Plant Physiol. 143: 188-98. PMID: 17098854
  3. Chromatographic analysis of salicylic compounds in different species of the genus Salix.  |  Pobłocka-Olech, L., et al. 2007. J Sep Sci. 30: 2958-66. PMID: 17880029
  4. Functional analysis of LjSUT4, a vacuolar sucrose transporter from Lotus japonicus.  |  Reinders, A., et al. 2008. Plant Mol Biol. 68: 289-99. PMID: 18618272
  5. Plant signal molecules activate the syrB gene, which is required for syringomycin production by Pseudomonas syringae pv. syringae.  |  Mo, YY. and Gross, DC. 1991. J Bacteriol. 173: 5784-92. PMID: 1885550
  6. Requirement of a reactive aldehyde moiety for aldehyde-mediated protection against cis-dichlorodiammineplatinum-induced cell inactivation.  |  Dornish, JM. and Pettersen, EO. 1990. Biochem Pharmacol. 39: 309-18. PMID: 2302256
  7. Identification of rice Os4BGlu13 as a β-glucosidase which hydrolyzes gibberellin A4 1-O-β-d-glucosyl ester, in addition to tuberonic acid glucoside and salicylic acid derivative glucosides.  |  Hua, Y., et al. 2015. Arch Biochem Biophys. 583: 36-46. PMID: 26241499
  8. Anticancer potency of copper(II) complexes of thiosemicarbazones.  |  Singh, NK., et al. 2020. J Inorg Biochem. 210: 111134. PMID: 32673842
  9. Determination of antimicrobial and antimutagenic properties of some Schiff bases.  |  Ogutcu, H., et al. 2021. An Acad Bras Cienc. 93: e20191432. PMID: 34287457
  10. Phenylglucosides and the Na+/glucose cotransporter (SGLT1): analysis of interactions.  |  Lostao, MP., et al. 1994. J Membr Biol. 142: 161-70. PMID: 7884808

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Helicin, 2 g

sc-221712
2 g
$300.00