Date published: 2025-9-18

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Guanine (CAS 73-40-5)

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Alternate Names:
2-Amino-6-hydroxypurine; 2-Aminohypoxanthine
Application:
Guanine is a nucleobase incorporated into biological nucleic acids
CAS Number:
73-40-5
Purity:
≥99%
Molecular Weight:
151.13
Molecular Formula:
C5H5N5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Guanine is a nucleobase incorporated into biological nucleic acids, such as RNA and DNA. Guanine, a purine derivative, plays a vital role in various biochemical processes, including transcription, replication, and translation. In laboratory applications, guanine serves as useful to investigate protein structure and function. Moreover, it enables researchers to explore the impact of mutations on gene expression.


Guanine (CAS 73-40-5) References

  1. Monovalent cation induced structural transitions in telomeric DNAs: G-DNA folding intermediates.  |  Hardin, CC., et al. 1991. Biochemistry. 30: 4460-72. PMID: 2021636
  2. Strong-field ionization of sputtered molecules for biomolecular imaging.  |  Willingham, D., et al. 2009. Chem Phys Lett. 468: 264-269. PMID: 20428490
  3. Capillary electrophoretic determination of DNA damage markers: content of 8-hydroxy-2'-deoxyguanosine and 8-nitroguanine in urine.  |  Li, MJ., et al. 2011. J Chromatogr B Analyt Technol Biomed Life Sci. 879: 3818-22. PMID: 22098717
  4. Monitoring guanine photo-oxidation by enantiomerically resolved Ru(II) dipyridophenazine complexes using inosine-substituted oligonucleotides.  |  Keane, PM., et al. 2015. Faraday Discuss. 185: 455-69. PMID: 26426601
  5. Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences.  |  Benasutti, M., et al. 1988. Biochemistry. 27: 472-81. PMID: 2831961
  6. Sublimation thermodynamics of nucleobases derived from fast scanning calorimetry.  |  Abdelaziz, A., et al. 2020. Phys Chem Chem Phys. 22: 838-853. PMID: 31840715
  7. Products of Oxidative Guanine Damage Form Base Pairs with Guanine.  |  Kino, K., et al. 2020. Int J Mol Sci. 21: PMID: 33076559
  8. LC-MS-based metabolomics reveals metabolite dynamic changes during irradiation of goat meat.  |  Jia, W., et al. 2021. Food Res Int. 150: 110721. PMID: 34865750
  9. Targeted and untargeted metabolomic analyses and biological activity of Tibetan tea.  |  Liu, Y., et al. 2022. Food Chem. 384: 132517. PMID: 35228002
  10. Endogenous benzoic acid interferes with the signatures of amino acids and thiol compounds through perturbing N-methyltransferase, glutamate-cysteine ligase, and glutathione S-transferase activity in dairy products.  |  Jia, W., et al. 2022. Food Res Int. 161: 111857. PMID: 36192981
  11. Modification-free electrochemical approach for sensitive monitoring of purine DNA bases: Simultaneous determination of guanine and adenine in biological samples using boron-doped diamond electrode  |  Švorc, Ľ., & Kalcher, K. 2014. Sensors and Actuators B: Chemical. 194: 332-342.
  12. The influencing mechanism of acidity on the oxidation peak currents of guanine and uric acid: hydrogen bond catalysis and degree of auxiliary electrode reduction reaction  |  Li, J., Gao, F., Shangguan, E., & Li, Q. 2014. Electrochimica Acta. 136: 377-384.
  13. Metabolomics and electronic tongue reveal the effects of different storage years on metabolites and taste quality of Oolong Tea  |  L Sun, S Zhang, Q Li, E Yuan, R Chen, F Yan, X Lai. 2023. Food Control. 152: 109847.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Guanine, 25 g

sc-211573
25 g
$21.00