Molecular structure of Glycitin, CAS Number: 40246-10-4
Glycitin (CAS 40246-10-4)
Alternate Names:
Glycitein 7-O-β-glucoside; 4′,7-Dihydroxy 6-methoxyisoflavone 7-O-glucoside; 4H-1-Benzopyran-4-one
Application:
Glycitin is a soy isoflavone
CAS Number:
40246-10-4
Purity:
≥98%
Molecular Weight:
446.41
Molecular Formula:
C22H22O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Glycitin, a synthetic glycoside derived from glucose through a glycosidic bond, is a soy isoflavone present in its glucoside form. Notably, a study conducted on a rat model demonstrated the effectiveness of glycitin in preventing bone loss and reversing unfavorable changes in lipid metabolism observed in the model. The presence of glycosidic bonds in glycitin is implicated in the binding of molecules to receptors, potentially accounting for some of the biological effects attributed to this compound. Furthermore, glycosidic bonds are believed to play a role in regulating cellular processes such as gene expression and cell division.
Glycitin (CAS 40246-10-4) References
- Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin. | Uesugi, T., et al. 2001. Biol Pharm Bull. 24: 368-72. PMID: 11305597
- Stabilities of daidzin, glycitin, genistin, and generation of derivatives during heating. | Xu, Z., et al. 2002. J Agric Food Chem. 50: 7402-6. PMID: 12452666
- Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. | Li, XH., et al. 2005. Acta Pharmacol Sin. 26: 1081-6. PMID: 16115375
- Anti-obese and anti-diabetic effects of a mixture of daidzin and glycitin on C57BL/6J mice fed with a high-fat diet. | Zang, Y., et al. 2015. Biosci Biotechnol Biochem. 79: 117-23. PMID: 25209298
- Soy Isoflavone Glycitin (4'-Hydroxy-6-Methoxyisoflavone-7-D-Glucoside) Promotes Human Dermal Fibroblast Cell Proliferation and Migration via TGF-β Signaling. | Kim, YM., et al. 2015. Phytother Res. 29: 757-69. PMID: 25758427
- Phytoestrogen Metabolism by Adult Human Gut Microbiota. | Gaya, P., et al. 2016. Molecules. 21: PMID: 27517891
- Glycitin regulates osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells. | Zhang, L., et al. 2016. Exp Ther Med. 12: 3063-3067. PMID: 27882117
- TMF and glycitin act synergistically on keratinocytes and fibroblasts to promote wound healing and anti-scarring activity. | Seo, GY., et al. 2017. Exp Mol Med. 49: e302. PMID: 28303029
- The conversion and deglycosylation of isoflavones and anthocyanins in black soymilk process. | Hsiao, YH. and Hsieh, JF. 2018. Food Chem. 261: 8-14. PMID: 29739609
- Glycitin alleviates lipopolysaccharide-induced acute lung injury via inhibiting NF-κB and MAPKs pathway activation in mice. | Chen, Y., et al. 2019. Int Immunopharmacol. 75: 105749. PMID: 31306981
- Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice. | Wang, W., et al. 2020. Inflammation. 43: 1312-1322. PMID: 32222871
- The Poly-Glutamate Motif of GmMATE4 Regulates Its Isoflavone Transport Activity. | Ku, YS., et al. 2022. Membranes (Basel). 12: PMID: 35207127
- Identifying Candidate Flavonoids for Non-Alcoholic Fatty Liver Disease by Network-Based Strategy. | Lee, WY., et al. 2022. Front Pharmacol. 13: 892559. PMID: 35721123
- Understanding hypocholesterolemic activity of soy isoflavones: Completing the puzzle through computational simulations. | Hermanto, FE., et al. 2022. J Biomol Struct Dyn. 1-7. PMID: 36443895
- Spectrum-effect relationship study to reveal the pharmacodynamic substances in Flos Puerariae-Semen Hoveniae medicine pair for the treatment of alcohol-induced liver damage. | Zhang, H., et al. 2023. J Ethnopharmacol. 116628. PMID: 37196817
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glycitin, 5 mg | sc-203420 | 5 mg | $132.00 | |||
Glycitin, 25 mg | sc-203420A | 25 mg | $519.00 |