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Ginkgolic acid C15:1 (CAS 22910-60-7) - chemical structure image
Molecular structure of Ginkgolic acid C15:1, CAS Number: 22910-60-7
Ginkgolic acid C15:1 (CAS 22910-60-7) - chemical structure image
Molecular structure of Ginkgolic acid C15:1, CAS Number: 22910-60-7
Molecular structure of Ginkgolic acid C15:1, CAS Number: 22910-60-7

Ginkgolic acid C15:1 (CAS 22910-60-7)

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Alternate Names:
6-[(8Z)-Pentadecenyl]-salicylic acid; Ginkgolic acid I
CAS Number:
22910-60-7
Purity:
≥98%
Molecular Weight:
346.50
Molecular Formula:
C22H34O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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SDS & Certificate of Analysis

Ginkgolic acid C15:1 is a naturally occurring alkylphenol found in ginkgo trees. It is primarily used in botanical and agricultural research, particularly in studies focusing on plant defense mechanisms against microbial infection and herbivory. In phytochemistry, ginkgolic acid C15:1 is studied for its role in the complex mixture of phytochemicals that contribute to the unique properties of ginkgo extracts. Researchers also investigate the compound′s allelopathic effects, where it may inhibit the growth of surrounding plant species, thus affecting biodiversity and plant community dynamics. In research related to natural products, ginkgolic acid C15:1 is examined for its potential as a lead compound for the development of bioactive substances. Additionally, its presence in ginkgo products is monitored due to its allergenic potential, which is significant for understanding environmental and health impacts. The specificity of the C15:1 side chain in ginkgolic acid provides a particular interest for researchers studying the structure-activity relationship of these compounds.


Ginkgolic acid C15:1 (CAS 22910-60-7) References

  1. A simple HPLC-UV method for the assay of ginkgolic acids in Ginkgo biloba extracts.  |  Fuzzati, N., et al. 2003. Fitoterapia. 74: 247-56. PMID: 12727489
  2. Ginkgolic acids and Ginkgo biloba extract inhibit Escherichia coli O157:H7 and Staphylococcus aureus biofilm formation.  |  Lee, JH., et al. 2014. Int J Food Microbiol. 174: 47-55. PMID: 24457153
  3. Ginkgolic Acid Inhibits Invasion and Migration and TGF-β-Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation.  |  Baek, SH., et al. 2017. J Cell Physiol. 232: 346-354. PMID: 27177359
  4. The antibacterial activity and mechanism of ginkgolic acid C15:1.  |  Hua, Z., et al. 2017. BMC Biotechnol. 17: 5. PMID: 28088196
  5. The catalytic activity for ginkgolic acid biodegradation, homology modeling and molecular dynamic simulation of salicylic acid decarboxylase.  |  Hu, Y., et al. 2018. Comput Biol Chem. 75: 82-90. PMID: 29751208
  6. Ginkgolic acid exerts an anti-inflammatory effect in human umbilical vein endothelial cells induced by ox-LDL.  |  Li, J., et al. 2018. Pharmazie. 73: 408-412. PMID: 30001776
  7. Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial.  |  Chassagne, F., et al. 2019. Front Microbiol. 10: 775. PMID: 31057504
  8. Inhibiting SUMO1-mediated SUMOylation induces autophagy-mediated cancer cell death and reduces tumour cell invasion via RAC1.  |  Lorente, M., et al. 2019. J Cell Sci. 132: PMID: 31578236
  9. Application of targeted 2D planar chromatography in the control of ginkgolic acids in some herbal drugs and dietary supplements.  |  Migas, P., et al. 2020. Acta Pharm. 70: 201-213. PMID: 31955143
  10. Enzymatic degradation of ginkgolic acid by laccase immobilized on novel electrospun nanofiber mat.  |  Chen, HY., et al. 2020. J Sci Food Agric. 100: 2705-2712. PMID: 32003007
  11. Profile of the main bioactive compounds and in vitro biological activity of different solvent extracts from Ginkgo biloba exocarp.  |  Cui, N., et al. 2020. RSC Adv. 10: 45105-45111. PMID: 35516276
  12. Effects of ginkgolic acid(C15:1)on biofilm formation, pathogenic factor production and quorum sensing of Pseudomonas aeruginosa.  |  Suo, A., et al. 2022. Microb Pathog. 173: 105813. PMID: 36202349
  13. Quality evaluation of ginkgo biloba leaves based on non-targeted metabolomics and representative ingredient quantification.  |  Gao, H., et al. 2023. J Chromatogr B Analyt Technol Biomed Life Sci. 1214: 123549. PMID: 36481725
  14. Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay.  |  Xiang, Y., et al. 2023. Int J Biol Macromol. 226: 780-792. PMID: 36521705
  15. Site-Directed Mutation of Salicylate Decarboxylase Gene and Mechanism of Ginkgo Acid Decarboxylation.  |  Song, Y., et al. 2023. Protein J. 42: 1-13. PMID: 36527585

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ginkgolic acid C15:1, 5 mg

sc-235249
5 mg
$306.00

Do you have any solubility information of this compound?

Asked by: two2igm05
Thank you for your question. Ginkgolic acid C15:1 is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of ginkgolic acid C15:1 in ethanol and DMF is approximately 50 mg/ml and approximately 30 mg/ml in DMSO. Ginkgolic acid C15:1 is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, ginkgolic acid C15:1 should first be dissolved in ethanol and then diluted with the aqueous buffer of choice. Ginkgolic acid C15:1 has a solubility of approximately 0.5 mg/ml in a 1:1 solution of ethanol:PBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2016-12-29
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