Date published: 2026-2-25

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Galangin (CAS 548-83-4)

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Alternate Names:
3,5,7-Trihydroxyflavone
Application:
Galangin is a flavanoid that has anti breast cancer properties in vitro
CAS Number:
548-83-4
Purity:
≥98%
Molecular Weight:
270.24
Molecular Formula:
C15H10O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Galangin is a flavonoid compound found in the roots of Alpinia officinarum and other plants within the ginger family. It exhibits a range of biological activities through its interaction with cellular processes and molecular pathways. Mechanistically, galangin modulates enzyme activities, influences gene expression, and interacts with cellular receptors, thereby impacting signaling pathways relevant to inflammation, oxidative stress, and cell proliferation. In research applications, it serves as a tool for investigating the cellular and molecular bases of these processes, offering insights into the regulation of cellular defense mechanisms against oxidative damage and the modulation of inflammatory responses. Its ability to interfere with the proliferation of various cell lines also positions galangin as a valuable compound for studies aimed at understanding the mechanisms underlying cell growth and the potential inhibitory effects on the propagation of certain cell types. Through these interactions, galangin contributes to the broader understanding of the cellular and molecular underpinnings of various biological processes, making it a compound of interest in the exploration of natural product-based interventions in cellular and molecular biology research.


Galangin (CAS 548-83-4) References

  1. Antimicrobial activity of flavonoids.  |  Cushnie, TP. and Lamb, AJ. 2005. Int J Antimicrob Agents. 26: 343-56. PMID: 16323269
  2. Chemopreventive mechanisms of galangin against hepatocellular carcinoma: A review.  |  Fang, D., et al. 2019. Biomed Pharmacother. 109: 2054-2061. PMID: 30551461
  3. The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.  |  Kong, Y., et al. 2019. Front Oncol. 9: 942. PMID: 31612107
  4. Bee Products in Dermatology and Skin Care.  |  Kurek-Górecka, A., et al. 2020. Molecules. 25: PMID: 32012913
  5. Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils.  |  Guan, X., et al. 2021. Life Sci. 264: 118660. PMID: 33127512
  6. Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats.  |  Abukhalil, MH., et al. 2021. Biomed Pharmacother. 138: 111410. PMID: 33752930
  7. Galangin Inhibits Gastric Cancer Growth Through Enhancing STAT3 Mediated ROS Production.  |  Liang, X., et al. 2021. Front Pharmacol. 12: 646628. PMID: 33981228
  8. A comprehensive review on chemotherapeutic potential of galangin.  |  Rampogu, S., et al. 2021. Biomed Pharmacother. 141: 111808. PMID: 34175820
  9. Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets.  |  Tuli, HS., et al. 2022. Exp Biol Med (Maywood). 247: 345-359. PMID: 34904901
  10. Galangin Reverses H2O2-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling.  |  Lee, JJ., et al. 2022. Int J Mol Sci. 23: PMID: 35163314
  11. Galangin reduces vascular endothelial cell dysfunction via Heme oxygenase-1 signaling.  |  Qian, Z. and Suo, R. 2022. Vascular. 17085381221084806. PMID: 35321597
  12. Galangin alleviates rheumatoid arthritis in rats by downregulating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway.  |  Deng, X., et al. 2022. Bioengineered. 13: 11192-11201. PMID: 35485325
  13. Galangin inhibited ferroptosis through activation of the PI3K/AKT pathway in vitro and in vivo.  |  Chen, K., et al. 2022. FASEB J. 36: e22569. PMID: 36183339
  14. Galangin as an inflammatory response modulator: An updated overview and therapeutic potential.  |  Thapa, R., et al. 2023. Chem Biol Interact. 378: 110482. PMID: 37044286

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Galangin, 25 mg

sc-235240
25 mg
$133.00