Friedelin (CAS 559-74-0)
QUICK LINKS
Friedelin is a triterpenoid compound that is a subject of interest in the field of natural products research. This compound is analyzed for its role in the chemical ecology of the plants that produce it, often serving as a protective agent against herbivores and pathogens. In research concerning plant biology, friedelin is studied for its contribution to the structural integrity of plant waxes and its impact on the water repellency of leaf surfaces. Additionally, its potential as a precursor for the synthesis of chemically interesting derivatives makes it a candidate for studies in organic synthesis. Environmental scientists also examine friedelin as a biomarker in paleobotany and geochemistry to reconstruct past vegetation and climate conditions, based on its preservation in geological samples.
Friedelin (CAS 559-74-0) References
- Antifungal activity of triterpenoid isolated from Azima tetracantha leaves. | Duraipandiyan, V., et al. 2010. Folia Histochem Cytobiol. 48: 311-3. PMID: 20675291
- Friedelane triterpenes from Celastrus vulcanicola as photosynthetic inhibitors. | Torres-Romero, D., et al. 2010. J Agric Food Chem. 58: 10847-54. PMID: 20873773
- Friedelin and lanosterol from Garcinia prainiana stimulated glucose uptake and adipocytes differentiation in 3T3-L1 adipocytes. | Susanti, D., et al. 2013. Nat Prod Res. 27: 417-24. PMID: 22988818
- Effects of friedelin on the intestinal permeability and bioavailability of apigenin. | Lee, JA., et al. 2017. Pharmacol Rep. 69: 1044-1048. PMID: 28939344
- Friedelin in Maytenus ilicifolia Is Produced by Friedelin Synthase Isoforms. | Alves, TB., et al. 2018. Molecules. 23: PMID: 29558378
- In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. | Wei, J., et al. 2018. Pharm Biol. 56: 363-367. PMID: 30122094
- CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway. | Bicalho, KU., et al. 2019. Plant Cell Physiol. 60: 2510-2522. PMID: 31350564
- Friedelin inhibits the growth and metastasis of human leukemia cells via modulation of MEK/ERK and PI3K/AKT signalling pathways. | Chang, W., et al. 2020. J BUON. 25: 1594-1599. PMID: 32862609
- Friedelin exhibits antidiabetic effect in diabetic rats via modulation of glucose metabolism in liver and muscle. | Sunil, C., et al. 2021. J Ethnopharmacol. 268: 113659. PMID: 33271243
- The influence of friedelin, resinone, tingenone and betulin of compounds on chondrogenic differentiation of porcine adipose-derived mesenchymal stem cells (pADMSCs). | Razwinani, M. and Motaung, KS. 2022. Biochimie. 196: 234-242. PMID: 35121053
- Friedelin Alleviates the Pathogenesis of Collagenase-Induced Tendinopathy in Mice by Promoting the Selective Autophagic Degradation of p65. | Jiang, H., et al. 2022. Nutrients. 14: PMID: 35458235
- Friedelin Attenuates Neuronal Dysfunction and Memory Impairment by Inhibition of the Activated JNK/NF-κB Signalling Pathway in Scopolamine-Induced Mice Model of Neurodegeneration. | Sandhu, M., et al. 2022. Molecules. 27: PMID: 35889382
- Friedelin, a novel inhibitor of CYP17A1 in prostate cancer from Cassia tora. | Joshi, BP., et al. 2022. J Biomol Struct Dyn. 1-26. PMID: 36373336
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Friedelin, 1 g | sc-252840 | 1 g | $400.00 |