Date published: 2026-1-6

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Flubendiamide (CAS 272451-65-7)

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Application:
Flubendiamide is an insecticide
CAS Number:
272451-65-7
Molecular Weight:
682.39
Molecular Formula:
C23H22F7IN2O4S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Flubendiamide mechanism of action may involve targeting and binding to the ryanodine receptor in insect muscle cells, leading to the disruption of calcium release and ultimately causing paralysis and death in the targeted pests. Flubendiamide may selectively and effectively control the population of certain insect species by interfering with their muscle function at the molecular level. This disruption of calcium release ultimately leads to the incapacitation of the insects, making flubendiamide useful study subject for pest control in agricultural and research applications.


Flubendiamide (CAS 272451-65-7) References

  1. Flubendiamide, a novel Ca2+ channel modulator, reveals evidence for functional cooperation between Ca2+ pumps and Ca2+ release.  |  Masaki, T., et al. 2006. Mol Pharmacol. 69: 1733-9. PMID: 16481391
  2. Molecular characterization of flubendiamide sensitivity in the lepidopterous ryanodine receptor Ca(2+) release channel.  |  Kato, K., et al. 2009. Biochemistry. 48: 10342-52. PMID: 19807072
  3. Residual behaviour and risk assessment of flubendiamide on chickpea (Cicer arietinum L.).  |  Singh, G., et al. 2011. Chemosphere. 84: 1416-21. PMID: 21596421
  4. Flubendiamide transport through packed soil columns.  |  Das, SK. and Mukherjee, I. 2012. Bull Environ Contam Toxicol. 88: 229-33. PMID: 22002178
  5. Safety evaluation of flubendiamide and its metabolites on cabbage and persistence in soil in different agroclimatic zones of India.  |  Sharma, KK., et al. 2014. Environ Monit Assess. 186: 3633-9. PMID: 24497081
  6. Biodegradation of flubendiamide by a newly isolated Chryseobacterium sp. strain SSJ1.  |  Jadhav, SS. and David, M. 2016. 3 Biotech. 6: 31. PMID: 28330102
  7. Evaluation of flubendiamide-induced mitochondrial dysfunction and metabolic changes in Helicoverpa armigera (Hubner).  |  Nareshkumar, B., et al. 2017. Arch Insect Biochem Physiol. 96: PMID: 28631341
  8. Flubendiamide affects visual and locomotory activities of Drosophila melanogaster for three successive generations (P, F1 and F2).  |  Sarkar, S., et al. 2018. Invert Neurosci. 18: 6. PMID: 29700671
  9. Flubendiamide induces transgenerational compound eye alterations in Drosophila melanogaster.  |  Sarkar, S. and Roy, S. 2017. Interdiscip Toxicol. 10: 142-147. PMID: 30147421
  10. Flubendiamide Enhances Adipogenesis and Inhibits AMPKα in 3T3-L1 Adipocytes.  |  Sun, Q., et al. 2018. Molecules. 23: PMID: 30424524
  11. In vitro and in vivo effects of flubendiamide and copper on cyto-genotoxicity, oxidative stress and spleen histology of rats and its modulation by resveratrol, catechin, curcumin and α-tocopherol.  |  Mandil, R., et al. 2020. BMC Pharmacol Toxicol. 21: 29. PMID: 32326976
  12. Flubendiamide, the first phthalic acid diamide insecticide, impairs neuronal calcium signalling in the honey bee's antennae.  |  Kadala, A., et al. 2020. J Insect Physiol. 125: 104086. PMID: 32628959
  13. Bioaccumulation and toxicity effects of flubendiamide in zebrafish (Danio rerio).  |  Meng, Z., et al. 2022. Environ Sci Pollut Res Int. 29: 26900-26909. PMID: 34860341
  14. Rapid and sensitive detection of flubendiamide in grapes and tomatoes using a colloidal gold immunochromatography assay.  |  Xu, X., et al. 2022. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 39: 1843-1854. PMID: 36103598
  15. Flubendiamide induced genetic and cellular damages directly influence the life cycle of the oriental leaf worm, Spodoptera litura.  |  Jameel, M., et al. 2023. Pestic Biochem Physiol. 193: 105448. PMID: 37248017

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Flubendiamide, 100 mg

sc-235144
100 mg
$159.00