Ethylmalonic acid (CAS 601-75-2)
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Ethylmalonic acid is frequently used in research focused on metabolic disorders and biochemical pathways involving short-chain fatty acids. This compound is instrumental in studying enzymatic processes and metabolic flux analysis, particularly in the context of fatty acid oxidation. Researchers utilize ethylmalonic acid to explore its biochemical behavior and interactions within various metabolic pathways, which helps to elucidate the underlying causes of metabolic anomalies. Additionally, it is used in studies aimed at understanding the accumulation and effects of organic acids in organisms. The research involving ethylmalonic acid enhances the understanding of metabolic diseases and aids in the exploration of potential biochemical markers.
Ethylmalonic acid (CAS 601-75-2) References
- Chronic early postnatal administration of ethylmalonic acid to rats causes behavioral deficit. | Schuck, PF., et al. 2009. Behav Brain Res. 197: 364-70. PMID: 18950661
- Promotion of lipid and protein oxidative damage in rat brain by ethylmalonic acid. | Schuck, PF., et al. 2010. Neurochem Res. 35: 298-305. PMID: 19757035
- Ethylmalonic acid impairs brain mitochondrial succinate and malate transport. | Amaral, AU., et al. 2012. Mol Genet Metab. 105: 84-90. PMID: 22133302
- Ethylmalonic acid modulates Na+, K(+)-ATPase activity and mRNA levels in rat cerebral cortex. | Schuck, PF., et al. 2013. Synapse. 67: 111-7. PMID: 23161776
- Ethylmalonic acid induces permeability transition in isolated brain mitochondria. | Cecatto, C., et al. 2014. Neurotox Res. 26: 168-78. PMID: 24557940
- Brain and muscle redox imbalance elicited by acute ethylmalonic acid administration. | Schuck, PF., et al. 2015. PLoS One. 10: e0126606. PMID: 26010931
- Taurine, glutamic acid and ethylmalonic acid as important metabolites for detecting human breast cancer based on the targeted metabolomics. | Wang, X., et al. 2018. Cancer Biomark. 23: 255-268. PMID: 30103303
- Capillary electrophoresis with capacitively coupled contactless conductivity detection for the determination of urinary ethylmalonic acid for the diagnosis of ethylmalonic aciduria. | Özçelik, S., et al. 2020. J Sep Sci. 43: 1365-1371. PMID: 31958360
- Mitochondrial Dysfunction and Redox Homeostasis Impairment as Pathomechanisms of Brain Damage in Ethylmalonic Encephalopathy: Insights from Animal and Human Studies. | Grings, M., et al. 2022. Cell Mol Neurobiol. 42: 565-575. PMID: 33034777
- An Unusually High Excretion of Ethylmalonic Acid in a Patient with Multiple Acyl-CoA Dehydrogenase Deficiency. | De Biase, I., et al. 2021. Clin Chem. 67: 1290-1292. PMID: 34470039
- Multiplexed LC-MS/MS analysis of methylsuccinic acid, ethylmalonic acid, and glutaric acid in plasma and urine. | Peng, KW., et al. 2022. Anal Biochem. 645: 114604. PMID: 35217005
- The urinary excretion of ethylmalonic acid: what level requires further attention? | Duran, M., et al. 1983. Biochem Med. 29: 171-5. PMID: 6860317
- Ethylmalonic aciduria is associated with an amino acid variant of short chain acyl-coenzyme A dehydrogenase. | Corydon, MJ., et al. 1996. Pediatr Res. 39: 1059-66. PMID: 8725270
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ethylmalonic acid, 1 g | sc-279156A | 1 g | $20.00 | |||
Ethylmalonic acid, 5 g | sc-279156 | 5 g | $52.00 | |||
Ethylmalonic acid, 25 g | sc-279156B | 25 g | $133.00 | |||
Ethylmalonic acid, 100 g | sc-279156C | 100 g | $469.00 |