Date published: 2025-10-14

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Ethyl propionate (CAS 105-37-3)

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Alternate Names:
Ethyl propanoate; Propanoic acid, ethyl ester; Propionic ether
CAS Number:
105-37-3
Purity:
≥98%
Molecular Weight:
102.13
Molecular Formula:
C5H10O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl propionate, a chemical compound with the molecular formula C5H10O2, has been extensively studied in scientific research, particularly in the fields of organic chemistry, flavor chemistry, and environmental sciences. It is an ester that possesses a fruity, sweet aroma. Research has focused on investigating the synthesis of ethyl propionate and understanding its mechanisms of formation. Ethyl propionate can be synthesized through esterification reactions between ethanol and propionic acid, catalyzed by acid catalysts or enzymes. Studies have explored the factors influencing the yield and selectivity of ethyl propionate synthesis, such as reaction conditions, catalysts, and reaction kinetics. Furthermore, ethyl propionate has been used as a flavoring agent and fragrance ingredient. Research has examined its sensory properties, odor thresholds, and contributions to aroma profiles. Ethyl propionate is commonly employed to impart fruity and apple-like notes in various products. Additionally, its use as a solvent in organic synthesis has been investigated. The research applications of ethyl propionate contribute to advancements in organic chemistry, flavor formulation, and understanding the behavior of volatile organic compounds (VOCs). By exploring the mechanisms and applications of ethyl propionate, researchers aim to optimize its synthesis methods, develop new organic transformations, and gain insights into its sensory impact and environmental fate.


Ethyl propionate (CAS 105-37-3) References

  1. Atmospheric chemistry of ethyl propionate.  |  Andersen, VF., et al. 2012. J Phys Chem A. 116: 5164-79. PMID: 22524192
  2. Conformational preferences of ethyl propionate molecule: Raman, temperature dependent FTIR spectroscopic study aided by ab initio quantum chemical and Car-Parrinello molecular dynamics simulation studies.  |  Dutta, B., et al. 2013. J Phys Chem A. 117: 4838-50. PMID: 23713825
  3. Ethyl propionate: Synergistic kairomone for african palm weevil,Rhynchophorus phoenicis L. (Coleoptera: Curculionidae).  |  Gries, G., et al. 1994. J Chem Ecol. 20: 889-97. PMID: 24242203
  4. Photo Oxidation Reaction Kinetics of Ethyl Propionate with Cl Atom and Formation of Propionic Acid.  |  Cheramangalath Balan, R. and Rajakumar, B. 2018. J Phys Chem A. 122: 8274-8285. PMID: 30251856
  5. RIFM fragrance ingredient safety assessment, ethyl propionate, CAS Registry Number 105-37-3.  |  Api, AM., et al. 2022. Food Chem Toxicol. 167 Suppl 1: 113343. PMID: 35948143
  6. A FTIR and DFT Combination Study to Reveal the Mechanism of Eliminating the Azeotropy in Ethyl Propionate-n-Propanol System with Ionic Liquid Entrainer.  |  Zheng, YZ., et al. 2023. Int J Mol Sci. 24: PMID: 37445775
  7. Solvent-free enzymatic synthesis and evaluation of vanillyl propionate as an effective and biocompatible preservative.  |  Lee, Y., et al. 2023. Bioprocess Biosyst Eng. 46: 1579-1590. PMID: 37682355
  8. Methyl N,N-dimethylanthranilate and ethyl propionate: repellents effective against spotted wing drosophila, Drosophila suzukii.  |  Conroy, C., et al. 2024. Pest Manag Sci. 80: 3160-3171. PMID: 38348748
  9. Addition of dimethylsulphoxide to methyl-tert-butyl ether and ethyl propionate increases cholesterol dissolving capacity and cholesterol gall stone dissolution in vitro.  |  Bergman, JJ., et al. 1994. Gut. 35: 1653-8. PMID: 7828992
  10. Ethyl propionate is more effective and less cytotoxic than methyl tert-butyl ether for topical gallstone dissolution.  |  Zakko, SF., et al. 1997. Gastroenterology. 113: 232-7. PMID: 9207283

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl propionate, 25 ml

sc-214997
25 ml
$15.00

Ethyl propionate, 500 ml

sc-214997A
500 ml
$39.00