Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake. Palmitic acid also makes up approximately 25% of the total plasma fatty acids in plasma lipoproteins. Saturated fatty acids induce the expression of cyclooxygenase-2 and, after protein acylation, are used to confer lipid anchoring to a variety of signaling molecules. Palmitic acid ethyl ester is a neutral, lipid soluble form of the free acid. It is one of the fatty acid ethyl esters that increase cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol.
1. Santos, M.J., et al. 1995. Ann. Nutr. Metab. 39: 52-62. PMID: 7872656 2. Dietzen, D.J., et al. 1995. J. Biol. Chem. 270: 6838-6842. PMID: 7896831 3. Robinson, L.J., et al. 1995. Proc. Natl. Acad. Sci. U.S.A. 92: 11776-11780. PMID: 8524847 4. Topinka, J.R. and Bredt, D.S. 1998. Neuron. 20: 125-134. PMID: 9459448 5. Lee, J.Y., et al. 2001. J. Biol. Chem. 276: 16683-16689. PMID: 11278967 6. Miggin, S.M., et al. 2003. J. Biol. Chem. 278: 6947-6958. PMID: 12488443
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.