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Ethyl benzoate (CAS 93-89-0)

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Alternate Names:
Benzoic ether; Benzoic Acid Ethyl Ester
CAS Number:
93-89-0
Molecular Weight:
150.17
Molecular Formula:
C9H10O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl benzoate, an organic compound, finds extensive usage in the synthesis of various compounds, as well as in the production of drugs and fragrances. This colorless to pale yellow liquid emanates a sweet, balsamic odor, distinguishing it. Ethyl benzoate comprises an ethyl group attached to the benzoic acid molecule. This compound exhibits solubility in water and alcohols, broadening its applicability in diverse fields. Within the realms of scientific research, ethyl benzoate serves as useful. Its involvement in synthesizing underscores its significance. Moreover, it contributes to the creation of polymers, surfactants, and other materials. Serving as a solvent in organic synthesis and an intermediate in the production of other organic compounds, its versatility is evident. Despite its extensive use, the precise mechanism of action of ethyl benzoate remains enigmatic. It is conjectured to function as a proton acceptor, thereby facilitating its reactions with other molecules. Additionally, its role as a Lewis acid enables it to form covalent bonds with other substances. Furthermore, ethyl benzoate exhibits catalytic properties in specific reactions, enhancing their rate of progress. Overall, the multifaceted nature of ethyl benzoate ensures its continued relevance across various domains.


Ethyl benzoate (CAS 93-89-0) References

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  2. Effect of dietary glycine and benzoate level on benzoate metabolism in mink (Mustela vision), blue fox (Alopex lagopus), and raccoon dog (Nyctereutes procyonoides).  |  Pölönen, IJ., et al. 2000. J Anim Sci. 78: 976-86. PMID: 10784188
  3. Structural aspects of the effect of ethyl benzoates on caffeine contracture.  |  Friedman, HA. 1975. Eur J Pharmacol. 33: 295-9. PMID: 1183478
  4. Purification and properties of an esterase from Aspergillus nomius HS-1 degrading ethylene glycol dibenzoate.  |  Uchida, H., et al. 2003. FEMS Microbiol Lett. 223: 123-7. PMID: 12799010
  5. The hydrolysis of ethyl benzoate, diethyl phthalate and benzocaine in cetrimide solutions.  |  MITCHELL, AG. 1962. J Pharm Pharmacol. 14: 172-6. PMID: 14474617
  6. Identification of a cocaine esterase in a strain of Pseudomonas maltophilia.  |  Britt, AJ., et al. 1992. J Bacteriol. 174: 2087-94. PMID: 1551831
  7. Stability of benzoyl peroxide in aromatic ester-containing topical formulations.  |  Majekodunmi, BD., et al. 2007. Pharm Dev Technol. 12: 609-20. PMID: 18161634
  8. An isocratic reversed-phase high-performance liquid chromatographic method for the simultaneous determination of benzoyl peroxide and the related compounds benzoic acid, benzaldehyde, ethyl benzoate, methylparaben, and propylparaben in dermal preparations.  |  Ali, MS., et al. 2008. J AOAC Int. 91: 1025-36. PMID: 18980115
  9. Symmetry-based design for the chemoenzymatic synthesis of oseltamivir (Tamiflu) from ethyl benzoate.  |  Sullivan, B., et al. 2009. Angew Chem Int Ed Engl. 48: 4229-31. PMID: 19425033
  10. RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-0.  |  Api, AM., et al. 2019. Food Chem Toxicol. 127 Suppl 1: S172-S178. PMID: 30885715
  11. Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities.  |  Attalah, KM., et al. 2020. Bioorg Chem. 94: 103371. PMID: 31708230
  12. Macro- and microscopic alterations in 2 rabbit skin regions following topically repeated applications of benzoic acid n-alkyl esters.  |  Branca, M., et al. 1988. Contact Dermatitis. 19: 320-34. PMID: 3233952
  13. Antidiabetic, antioxidant, and anti-obesity effects of phenylthio-ethyl benzoate derivatives, and molecular docking study regarding α-amylase enzyme.  |  Jaradat, N., et al. 2022. Sci Rep. 12: 3108. PMID: 35210523
  14. Inhibition of Aspergillus growth and aflatoxin release by derivatives of benzoic acid.  |  Chipley, JR. and Uraih, N. 1980. Appl Environ Microbiol. 40: 352-7. PMID: 6781406

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl benzoate, 5 g

sc-239920
5 g
$22.00

Ethyl benzoate, 100 g

sc-239920A
100 g
$51.00