Date published: 2025-10-14

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Ethyl acetate (CAS 141-78-6)

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Application:
Ethyl acetate is a solvent used in extractions and column chromatography
CAS Number:
141-78-6
Molecular Weight:
88.11
Molecular Formula:
C4H8O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl acetate is an organic compound widely recognized for its distinctive sweet smell, akin to pears or certain glues, making it prominent in both industrial and research applications. As an ester derived from the reaction between ethanol and acetic acid, ethyl acetate is characterized by its excellent solvency properties, which make it ideal for use as a solvent in a variety of applications including coatings, inks, and adhesives. In the realm of research, ethyl acetate is particularly valued in organic chemistry where it is used as a polar aprotic solvent. Its ability to dissolve a wide range of organic compounds without participating in hydrogen bonding makes it a preferred choice for facilitating numerous types of chemical reactions and processes. This solvent is also extensively used in chromatography, including both column and thin-layer chromatography, as a mobile phase that helps in the separation of substances based on their different affinities towards the stationary phase. Additionally, ethyl acetate′s relatively low toxicity and fast evaporation rate make it useful in the preparation of samples for analysis, as it minimizes interference caused by solvent residues. In environmental research, ethyl acetate is studied for its biodegradability and potential impacts on air quality, contributing to a broader understanding of solvent emissions and their regulatory management.


Ethyl acetate (CAS 141-78-6) References

  1. Ethyl acetate extract from black tea prevents neuromuscular blockade by botulinum neurotoxin type A in vitro.  |  Satoh, E. 2005. Int J Food Sci Nutr. 56: 543-50. PMID: 16638658
  2. Evaluation of antioxidant potential of ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn.  |  Singh, R., et al. 2007. Food Chem Toxicol. 45: 1216-23. PMID: 17336438
  3. One-step isolation of γ-oryzanol from rice bran oil by non-aqueous hydrostatic countercurrent chromatography.  |  Angelis, A., et al. 2011. J Sep Sci. 34: 2528-37. PMID: 21780286
  4. Perspectives for the biotechnological production of ethyl acetate by yeasts.  |  Löser, C., et al. 2014. Appl Microbiol Biotechnol. 98: 5397-415. PMID: 24788328
  5. Ethyl acetate production by the elusive alcohol acetyltransferase from yeast.  |  Kruis, AJ., et al. 2017. Metab Eng. 41: 92-101. PMID: 28356220
  6. Perspectives for the microbial production of ethyl acetate.  |  Zhang, S., et al. 2020. Appl Microbiol Biotechnol. 104: 7239-7245. PMID: 32656615
  7. Inherent Ethyl Acetate Selectivity in a Trianglimine Molecular Solid.  |  He, D., et al. 2021. Chemistry. 27: 10589-10594. PMID: 33929053
  8. Metabolic engineering of Clostridium autoethanogenum for ethyl acetate production from CO.  |  Dykstra, JC., et al. 2022. Microb Cell Fact. 21: 243. PMID: 36419165
  9. Spaceflight Maximum Allowable Concentrations for Ethyl Acetate.  |  Williams, ES. and Ryder, VE. 2023. Aerosp Med Hum Perform. 94: 25-33. PMID: 36757222
  10. Development of a dual isotopes techniques and two-stage column chromatography to characterize the prostaglandin F2alpha, E2 and Thromboxane B2 formed by the guinea pig lung.  |  Giri, SN. and Krishna, GA. 1980. J Pharmacol Methods. 4: 335-53. PMID: 7009992

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl acetate, 4 L

sc-360246
4 L
$165.00
US: Only available in the US