Ergosterol (CAS 57-87-4)
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Ergosterol is a sterol compound that plays a fundamental role in the biology of fungi and protozoa, where it is a key component of cell membranes, akin to the role of cholesterol in animal cells. In research, ergosterol is often used as a biomarker for fungal biomass in ecological studies and as an indicator of fungal growth in various substrates. Its quantification in soil, for instance, helps in assessing the presence and activity of fungi in ecological studies. In laboratory applications, ergosterol is employed in experiments to understand membrane fluidity and integrity in fungal organisms, as its abundance and distribution within the membrane can influence the physical properties of the membrane. Additionally, its synthesis pathway is targeted by antifungal compounds; thus, ergosterol is central to studies aiming to explore or develop antifungal agents. Furthermore, the irradiation of ergosterol with ultraviolet light results in the formation of vitamin D2, an aspect that is used in the field of nutritional science to enhance the vitamin D content of foods and dietary supplements.
Ergosterol (CAS 57-87-4) References
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- Ergosterol-loaded poly(lactide-co-glycolide) nanoparticles with enhanced in vitro antitumor activity and oral bioavailability. | Zhang, HY., et al. 2016. Acta Pharmacol Sin. 37: 834-44. PMID: 27133301
- Ergosterol Peroxide: A Mushroom-Derived Compound with Promising Biological Activities-A Review. | Merdivan, S. and Lindequist, U. 2017. Int J Med Mushrooms. 19: 93-105. PMID: 28436318
- Development of ergosterol peroxide probes for cellular localisation studies. | Ling, T., et al. 2019. Org Biomol Chem. 17: 5223-5229. PMID: 31025693
- Cholecalciferol, Ergosterol, and Cholesterol Enhance the Antibiotic Activity of Drugs. | Andrade, JC., et al. 2018. Int J Vitam Nutr Res. 88: 244-250. PMID: 31124408
- Ergosterol peroxide suppresses influenza A virus-induced pro-inflammatory response and apoptosis by blocking RIG-I signaling. | Zhou, B., et al. 2019. Eur J Pharmacol. 860: 172543. PMID: 31323223
- Insights into Ergosterol Peroxide's Trypanocidal Activity. | Meza-Menchaca, T., et al. 2019. Biomolecules. 9: PMID: 31547423
- Effect of ergosterol on the interlamellar spacing of deuterated yeast phospholipid multilayers. | Luchini, A., et al. 2020. Chem Phys Lipids. 227: 104873. PMID: 31926858
- Ergosterol Peroxide from the Medicinal Mushroom Ganoderma lucidum Inhibits Differentiation and Lipid Accumulation of 3T3-L1 Adipocytes. | Jeong, YU. and Park, YJ. 2020. Int J Mol Sci. 21: PMID: 31936890
- Evaluation of ergosterol composition and esterification rate in fungi isolated from mangrove soil, long-term storage of broken spores, and two soils. | Dong, SJ., et al. 2020. Appl Microbiol Biotechnol. 104: 5461-5475. PMID: 32333053
- Anti-inflammatory ergosterol derivatives from the endophytic fungus Fusarium chlamydosporum. | Al-Rabia, MW., et al. 2021. Nat Prod Res. 35: 5011-5020. PMID: 32375510
- Isolation and characterization of ergosterol from Monascus anka for anti-lipid peroxidation properties. | Yongxia, Z., et al. 2020. J Mycol Med. 30: 101038. PMID: 33069573
- Ergosterol isolated from cloud ear mushroom (Auricularia polytricha) attenuates bisphenol A-induced BV2 microglial cell inflammation. | Sillapachaiyaporn, C., et al. 2022. Food Res Int. 157: 111433. PMID: 35761673
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ergosterol, 5 g | sc-205313 | 5 g | $131.00 | |||
Ergosterol, 10 g | sc-205313A | 10 g | $213.00 |