Molecular structure of Elaidic Acid, CAS Number: 112-79-8
Elaidic Acid (CAS 112-79-8)
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Alternate Names:
trans-Oleic Acid
Application:
Elaidic Acid is a monounsaturated trans-fatty acid that inhibits HHT and HETE formation in platelets
CAS Number:
112-79-8
Purity:
>98%
Molecular Weight:
282.5
Molecular Formula:
C18H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Elaidic acid is a trans-unsaturated fatty acid. In vitro investigations have been undertaken to delve into its impact on cell proliferation, apoptosis, and gene expression. Researchers have discovered that elaidic acid acts as an agonist for the peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor responsible for regulating lipid and glucose metabolism. Additionally, elaidic acid has been found to act as an agonist for the PPARα receptor.
Elaidic Acid (CAS 112-79-8) References
- Elaidic acid sustains LPS and TNF-alpha induced ICAM-1 and VCAM-I expression on human bone marrow endothelial cells (HBMEC). | Sanadgol, N., et al. 2010. Clin Biochem. 43: 968-72. PMID: 20451511
- Elaidic acid increases hepatic lipogenesis by mediating sterol regulatory element binding protein-1c activity in HuH-7 cells. | Shao, F. and Ford, DA. 2014. Lipids. 49: 403-13. PMID: 24481861
- Elaidic acid (EA) generates dysfunctional high-density lipoproteins and consumption of EA exacerbates hyperlipidemia and fatty liver change in zebrafish. | Park, KH., et al. 2014. Mol Nutr Food Res. 58: 1537-45. PMID: 24863413
- Elaidic acid and vaccenic acid in the plasma of pregnant women and umbilical blood plasma. | Jamioł-Milc, D., et al. 2015. Pomeranian J Life Sci. 61: 51-7. PMID: 27116856
- Elaidic Acid, a Trans-Fatty Acid, Enhances the Metastasis of Colorectal Cancer Cells. | Ohmori, H., et al. 2017. Pathobiology. 84: 144-151. PMID: 27832659
- Association between Serum Elaidic Acid Concentration and Insulin Resistance in Two Japanese Cohorts with Different Lifestyles. | Itcho, K., et al. 2017. J Atheroscler Thromb. 24: 1206-1214. PMID: 28484112
- Elaidic acid induces cell apoptosis through induction of ROS accumulation and endoplasmic reticulum stress in SH‑SY5Y cells. | Ma, WW., et al. 2017. Mol Med Rep. 16: 9337-9346. PMID: 29152653
- Association between plasma concentrations of elaidic acid, a major trans fatty acid, and depression in a nationally representative sample of U.S. adults. | Liu, B., et al. 2019. J Affect Disord. 249: 301-306. PMID: 30797122
- Elevated Serum Elaidic Acid Predicts Risk of Repeat Revascularization After Percutaneous Coronary Intervention in Japan. | Oshita, T., et al. 2019. Circ J. 83: 1032-1038. PMID: 30867359
- Serum elaidic acid concentration and risk of dementia: The Hisayama Study. | Honda, T., et al. 2019. Neurology. 93: e2053-e2064. PMID: 31645469
- Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X7-ROS-ASK1-p38 Axis in Microglial Cell Lines. | Hirata, Y., et al. 2020. Biol Pharm Bull. 43: 1562-1569. PMID: 32999166
- Elaidic acid induced NLRP3 inflammasome activation via ERS-MAPK signaling pathways in Kupffer cells. | Liu, H., et al. 2022. Biochim Biophys Acta Mol Cell Biol Lipids. 1867: 159061. PMID: 34610469
- Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study. | Jiaxin, H., et al. 2022. Front Nutr. 9: 1034841. PMID: 36570162
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Elaidic Acid, 50 mg | sc-205309 | 50 mg | $20.00 | |||
Elaidic Acid, 100 mg | sc-205309A | 100 mg | $39.00 |