Date published: 2026-3-27

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DL-Mevalonolactone (CAS 674-26-0)

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Alternate Names:
(±)-3-Hydroxy-3-methyl δ-valerolactone
Application:
DL-Mevalonolactone is a useful substrate for biological research purposes
CAS Number:
674-26-0
Purity:
≥97%
Molecular Weight:
130.14
Molecular Formula:
C6H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-Mevalonolactone is a useful substrate for biological research purposes. DL-Mevalonolactone, the δ-lactone variant of mevalonic acid, serves as a precursor in the mevalonate pathway. This compound is known to cause depolarization and swelling, reduce NADPH content and aconitase (ACO) activity, and promote the generation of malondialdehyde (MDA) in calcium-loaded rat brain mitochondria. Furthermore, DL-Mevalonolactone has the ability to counteract the decline in glucose uptake caused by simvastatin.


DL-Mevalonolactone (CAS 674-26-0) References

  1. Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity.  |  Withers, ST., et al. 2007. Appl Environ Microbiol. 73: 6277-83. PMID: 17693564

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-Mevalonolactone, 1 g

sc-211365
1 g
$156.00

DL-Mevalonolactone, 5 g

sc-211365A
5 g
$780.00