Date published: 2025-12-8

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Dimethyl sulfite (CAS 616-42-2)

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Alternate Names:
Methyl sulfite
CAS Number:
616-42-2
Molecular Weight:
110.13
Molecular Formula:
C2H6O3S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dimethyl sulfite is a chemical compound that sees application in diverse research areas, particularly in organic synthesis and material science. As a mild methylating agent, it is frequently employed in the methylation of alcohols, phenols, and amines, enabling chemists to study the influence of methyl groups on molecular properties and reactivity. Its use extends to the field of polymer chemistry, where it acts as a reagent in the modification of polymer chains, thus helping to tailor the physical characteristics of polymeric materials. Furthermore, researchers investigate the role of dimethyl sulfite in the synthesis of sulfonates, leveraging its sulfite moiety for the introduction of sulfur-containing functional groups. This compound is also a subject of interest in environmental chemistry, where its degradation mechanisms and potential impact on atmospheric chemistry are examined.


Dimethyl sulfite (CAS 616-42-2) References

  1. Reactions of Dimethyl Sulfite with Diorganotin Oxides. One-Pot Synthesis of Methoxydiorganotin Methanesulfonates through the Arbuzov Rearrangement, Spectroscopic Characterization of These Compounds and Their Derivatives, and X-ray Crystal Structures of n-Bu(2)Sn(X)OS(O)(2)Me (X = acac, bzbz, OH).  |  Narula, SP., et al. 1999. Inorg Chem. 38: 4777-4783. PMID: 11671205
  2. Derivatisation in gas chromatographic determination of acidic herbicides in aqueous environmental samples.  |  Rompa, M., et al. 2003. Anal Bioanal Chem. 377: 590-9. PMID: 12904959
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  4. Matrix isolation FTIR spectroscopic and theoretical study of dimethyl sulfite.  |  Borba, A., et al. 2005. J Phys Chem A. 109: 3578-86. PMID: 16839024
  5. Studies on electrochemical performances of novel electrolytes for wide-temperature-range lithium-ion batteries.  |  Li, S., et al. 2014. ACS Appl Mater Interfaces. 6: 4920-6. PMID: 24611743
  6. Laryngopharyngeal Reflux Has Negative Effects on Taste and Smell Functions.  |  Altundag, A., et al. 2016. Otolaryngol Head Neck Surg. 155: 117-21. PMID: 27048678
  7. Iodine-promoted ring-opening methylation of benzothiazoles with dimethyl sulfite.  |  Guo, YQ., et al. 2021. Chem Commun (Camb). 57: 1923-1926. PMID: 33496694
  8. Structural Evidence for Pnictogen-Centered Lewis Acidity in Cationic Platinum-Stibine Complexes Featuring Pendent Amino or Ammonium Groups.  |  Rodrigues, RR. and Gabbaï, FP. 2021. Molecules. 26: PMID: 33915809
  9. Palladium-Catalyzed Methylsulfonylation of Alkyl Halides Using Dimethyl Sulfite as SO2 Surrogate and Methyl Source.  |  Xin, YH., et al. 2021. J Org Chem. 86: 17496-17503. PMID: 34747609
  10. Effect of High-Voltage Additives on Formation of Solid Electrolyte Interphases in Lithium-Ion Batteries.  |  Chen, M., et al. 2022. Materials (Basel). 15: PMID: 35629689
  11. Lithium-Ion Batteries under Low-Temperature Environment: Challenges and Prospects.  |  Luo, H., et al. 2022. Materials (Basel). 15: PMID: 36431650
  12. Combined time-restricted feeding and cisplatin enhance the anti-tumor effects in cisplatin-resistant and -sensitive lung cancer cells.  |  Li, J., et al. 2022. Med Oncol. 40: 63. PMID: 36576605
  13. Analysis of the possible altering function of the septal organ in rats: a lesional and behavioral study.  |  Giannetti, N., et al. 1995. Physiol Behav. 58: 837-45. PMID: 8577878

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dimethyl sulfite, 100 g

sc-227898
100 g
$115.00