Molecular structure of DHEA, CAS Number: 53-43-0
DHEA (CAS 53-43-0)
See product citations (3)
Alternate Names:
Dehydro-epi-androsterone; (+)-Dehydroisoandrosterone; 3β-Hydroxy-5-androsten-17-one
Application:
DHEA is a negative modulator of GABAA receptors
CAS Number:
53-43-0
Purity:
≥98%
Molecular Weight:
288.43
Molecular Formula:
C19H28O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
DHEA is a major secretory steroidal product of the adrenal gland. DHEA and its sulfated metabolite, DHEA-S, are negative modulators of GABAA receptors. DHEA is an inhibitor of T-type Ca++ CP alpha 1G, T-type Ca++ CP alpha 1H and T-type Ca++ CP alpha 1I and an activator of Sigma Receptor, PXR and Estrogen Receptor.
DHEA (CAS 53-43-0) References
- Dehydroepiandrosterone (DHEA) supplementation for cognitive function . | Huppert, FA. and Van Niekerk, JK. 2001. Cochrane Database Syst Rev. CD000304. PMID: 11405958
- [Dehydroepiandrosterone (DHEA), review of its efficiency in the managing of the libido decrease and other symtoms of aging]. | Mendivil Dacal, JM. and Borges, VM. 2009. Actas Urol Esp. 33: 390-401. PMID: 19579890
- DHEA therapy in postmenopausal women: the need to move forward beyond the lack of evidence. | Genazzani, AR. and Pluchino, N. 2010. Climacteric. 13: 314-6. PMID: 20540592
- Dehydroepiandrosterone (DHEA): hypes and hopes. | Rutkowski, K., et al. 2014. Drugs. 74: 1195-207. PMID: 25022952
- The role of dehydroepiandrosterone (DHEA) in schizophrenia. | Vuksan-Ćusa, B., et al. 2016. Psychiatr Danub. 28: 30-3. PMID: 26938818
- Cortisol and DHEA in development and psychopathology. | Kamin, HS. and Kertes, DA. 2017. Horm Behav. 89: 69-85. PMID: 27979632
- Biotransformation of DHEA into 7α,15α-diOH-DHEA. | Li, H., et al. 2017. Methods Mol Biol. 1645: 289-295. PMID: 28710636
- The Effect of Statins on Levels of Dehydroepiandrosterone (DHEA) in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. | Yang, S., et al. 2019. Med Sci Monit. 25: 590-597. PMID: 30698163
- Arimistane: Degradation product or metabolite of 7-oxo-DHEA? | Martínez Brito, D., et al. 2021. Drug Test Anal. 13: 1430-1439. PMID: 33783974
- A review of dehydroepiandrosterone (DHEA). | Shealy, CN. 1995. Integr Physiol Behav Sci. 30: 308-13. PMID: 8788227
- Studies of dehydroepiandrosterone (DHEA) as a therapeutic agent in systemic lupus erythematosus. | Van Vollenhoven, RF. and McGuire, JL. 1996. Ann Med Interne (Paris). 147: 290-6. PMID: 8952750
- Dehydroepiandrosterone (DHEA) and systemic lupus erythematosus. | Derksen, RH. 1998. Semin Arthritis Rheum. 27: 335-47. PMID: 9662752
- Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DS) as therapeutic options in menopause. | Katz, S. and Morales, AJ. 1998. Semin Reprod Endocrinol. 16: 161-70. PMID: 9711682
Inhibitor of:
APIP, CH25H, CHST1, DAX-1, G6pd2, GABAA Rδ, GalNAc4ST-1, GK3P, Glucose-6-Phosphate Dehydrogenase, GPD2, MYBPC2, P5CRL, PGLS, rcRPE, SH-PTP1, SQRDL, SR-BI, Sulfotransferase (SULT1), SULT1A4, SULT1B1, SULT2A2, T-type Ca++ CP alpha 1G, T-type Ca++ CP alpha 1H, T-type Ca++ CP α 1I, TKTL2, TRIM56, TRMU, USF-2, and Vanin-1.Activator of:
11β-HSD1L, 17-β Estradiol, 17β-HSD, 17β-HSD14, 17β-HSD2, 17β-HSD3, 17β-HSD6, 3β-HSD, 3β-HSD3, ABP, AKR1D1, Androgen Receptor, ARA55, C4ST-3, CR1L, DAF-12, DD4, EG215895, EG545948, EG639025, EG665615, Estrogen Receptor, FHR-4, GABAA Rθ, GDF-9, Glut1, GlyR α2, IFITM5, IGF-IIR, Inhibin β-A, Kap, KRTAP2-3, KRTAP5-3, Latrophilin-3, MUP15, OAT5, PBR, PDK4, PGRMC1, PGRMC2, PHYH, PKLR, PXR, RIP15, SAPAP3, Sigma Receptor, SMR2, SMR3A, SPATA10, SRD5A2L2, SULT1C1, SULT1C3, SULT2A4, SULT2B10, Testosterone, TPST-2, UGT1A10, UGT3A1, UST, and ZIP9.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DHEA, 10 g | sc-202573 | 10 g | $111.00 | |||
| US: Only available in the US | ||||||