Date published: 2025-10-8

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Dazomet (CAS 533-74-4)

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Alternate Names:
3,5-Dimethyltetrahydro-1,3,5-thiadiazine-2-thione; Thiadiazine
Application:
Dazomet is a common soil fumigant
CAS Number:
533-74-4
Molecular Weight:
162.28
Molecular Formula:
C5H10N2S2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dazomet functions as a soil fumigant, used to control a wide range of soil-borne pests and pathogens in agricultural and horticultural applications. Its mechanism of action involves releasing a toxic gas when it comes into contact with moisture in the soil, effectively sterilizing the soil and eliminating harmful organisms. Dazomet acts by disrupting the cellular respiration process of microorganisms, may lead to their death and prevent the spread of diseases and pests. Dazomet works by inhibiting the activity of enzymes and proteins necessary for the survival of soil-borne pathogens, ultimately leading to their eradication. Its mechanism of action involves penetrating the soil and releasing toxic gases that target and destroy harmful organisms, making it effective for soil sterilization in various agricultural and horticultural applications.


Dazomet (CAS 533-74-4) References

  1. Evaluation of dazomet as fumigant for the control of brown root rot disease.  |  Fu, CH., et al. 2012. Pest Manag Sci. 68: 959-62. PMID: 22522815
  2. Synergistic Effect of Dazomet Soil Fumigation and Clonostachys rosea Against Cucumber Fusarium Wilt.  |  Tian, T., et al. 2014. Phytopathology. 104: 1314-21. PMID: 24941326
  3. Environmental Factors and Soil Amendment Affect the Decomposition Rate of Dazomet Fumigant.  |  Fang, W., et al. 2018. J Environ Qual. 47: 1223-1231. PMID: 30272792
  4. Responses of Nitrogen-Cycling Microorganisms to Dazomet Fumigation.  |  Fang, W., et al. 2018. Front Microbiol. 9: 2529. PMID: 30405582
  5. Effects of Sublabeled Rates of Dazomet and Metam-Sodium Applied Under Low-Permeability Films on Calonectria Microsclerotia Survival.  |  Aiello, D., et al. 2018. Plant Dis. 102: 782-789. PMID: 30673406
  6. Effects of Dazomet Fumigation on Soil Phosphorus and the Composition of phoD-Harboring Microbial Communities.  |  Huang, B., et al. 2020. J Agric Food Chem. 68: 5049-5058. PMID: 32134657
  7. Dazomet application suppressed watermelon wilt by the altered soil microbial community.  |  Zhu, F., et al. 2020. Sci Rep. 10: 21668. PMID: 33303943
  8. [Effects of dazomet fumigation on growth, biological characteristics of Malus hupehensis seedlings and soil environment].  |  Jiang, WT., et al. 2020. Ying Yong Sheng Tai Xue Bao. 31: 3085-3092. PMID: 33345510
  9. Chloropicrin alternated with dazomet improved the soil's physicochemical properties, changed microbial communities and increased strawberry yield.  |  Li, Q., et al. 2021. Ecotoxicol Environ Saf. 220: 112362. PMID: 34087650
  10. Site-Specific Controlled-Release Imidazolate Framework-8 for Dazomet Smart Delivery to Improve the Effective Utilization Rate and Reduce Biotoxicity.  |  Ren, L., et al. 2022. J Agric Food Chem. 70: 5993-6005. PMID: 35506688
  11. [Determination of dazomet and its metabolite methyl isothiocyanate residues in plant-derived foods by gas chromatography-triple quadrupole mass spectrometry].  |  Rong, J., et al. 2022. Se Pu. 40: 661-668. PMID: 35791605
  12. Effects of dazomet combined with Rhodopsesudomonas palustris PSB-06 on root-knot nematode, Meloidogyne incognita infecting ginger and soil microorganisms diversity.  |  Wang, D., et al. 2022. Front Microbiol. 13: 1021445. PMID: 36246285
  13. Application of microbial organic fertilizers promotes the utilization of nutrients and restoration of microbial community structure and function in rhizosphere soils after dazomet fumigation.  |  Huang, B., et al. 2022. Front Microbiol. 13: 1122611. PMID: 36741882
  14. In vivo studies on genotoxicity of a soil fumigant, dazomet.  |  Peluso, M., et al. 1998. Environ Mol Mutagen. 32: 179-84. PMID: 9776181

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dazomet, 250 mg

sc-252662
250 mg
$97.00