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D-Ribonolactone (CAS 5336-08-3)

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Alternate Names:
D-(+)-Ribonic Acid γ-Lactone; D-(+)-Ribonolactone; D-Ribono-1,4-lactone
Application:
D-Ribonolactone is a sugar lactone and β-galactosidase inhibitor
CAS Number:
5336-08-3
Purity:
≥97%
Molecular Weight:
148.11
Molecular Formula:
C5H8O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Ribonolactone, a cyclic sugar lactone derived from ribose, has emerged as a crucial molecule in various research endeavors, particularly in the fields of biochemistry, enzymology, and organic synthesis. Its chemical structure, characterized by a five-membered lactone ring, renders it conducive for investigating carbohydrate chemistry and enzymatic transformations. In research, D-Ribonolactone serves as a substrate for enzymes such as lactonases and lactonizing enzymes, which catalyze its hydrolysis to form D-ribose, a fundamental sugar molecule involved in numerous biological processes. This enzymatic hydrolysis mechanism is extensively studied to understand enzyme-substrate interactions, catalytic mechanisms, and substrate specificity, providing insights into enzyme kinetics and protein engineering strategies. Furthermore, D-Ribonolactone is employed as a precursor in the synthesis of ribose-containing compounds, including nucleosides, nucleotides, and carbohydrate derivatives, facilitating the development of novel biomolecules with potential applications in drug discovery, molecular biology, and chemical biology research. Its versatile role as a starting material in organic synthesis enables the construction of diverse chemical libraries and molecular probes for investigating biological systems and developing agents. Overall, D-Ribonolactone continues to be a valuable tool in scientific research, contributing to advancements in carbohydrate chemistry, enzymology, and synthetic biology.


D-Ribonolactone (CAS 5336-08-3) References

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  6. Sandwich injection and analyte protectants as a way to decrease the drift due to matrix effect between bracketing calibration in GC-MS/MS: A case study.  |  Soliman, M. 2021. Talanta. 225: 121970. PMID: 33592804
  7. Green synthesis of 1,5-dideoxy-1,5-imino-ribitol and 1,5-dideoxy-1,5-imino-DL-arabinitol from natural D-sugars over Au/Al2O3 and SO42-/Al2O3 catalysts.  |  Gao, H. and Fan, A. 2021. Sci Rep. 11: 16928. PMID: 34413372
  8. A facile and general entry to optically active pheromones and aromas with γ-alkyl-γ-lactone structures. A study of some lactone derivatives of pentoses†  |   and J. Cardellach, J. Font, R. M. Ortuño.: March/April 1984. Journal of heterocyclic chemistry. Volume21, Issue2: Pages 327-331.
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Ribonolactone, 5 g

sc-221517
5 g
$169.00