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D-Fructose 1,6-bisphosphate trisodium salt octahydrate (CAS 81028-91-3)

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Alternate Names:
D-Fructose 1,6-diphosphate trisodium salt; FDP-Na3H
Application:
D-Fructose 1,6-bisphosphate trisodium salt octahydrate is a common metabolic sugar that is an allosteric activator of enzymes such as pyruvate kinase
CAS Number:
81028-91-3
Purity:
≥98%
Molecular Weight:
550.18
Molecular Formula:
C6H11O12P23Na•8H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Fructose-1,6-bisphosphate, a common metabolic sugar, is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway. D-Fructose 1,6-bisphosphate trisodium salt octahydrate is an activator of PKLR and PKM2. D-Fructose 1,6-bisphosphate trisodium salt octahydrate is also a substrate of Aldolase, liver FBPaseand and muscle FBPase. It is an allosteric activator of enzymes such as pyruvate kinase and a substrate used to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1, 6-bisphosphatase(s). D-Fructose-1,6-bisphosphate is studied as a neuroprotective agent in brain injury.


D-Fructose 1,6-bisphosphate trisodium salt octahydrate (CAS 81028-91-3) References

  1. Fructose-1,6-bisphosphate does not preserve ATP in hypoxic-ischemic neonatal cerebrocortical slices.  |  Liu, J., et al. 2008. Brain Res. 1238: 230-8. PMID: 18725216
  2. Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle.  |  Denger, K., et al. 2014. Nature. 507: 114-7. PMID: 24463506
  3. Microwave-Assisted Hydrothermal Synthesis of Cellulose/Hydroxyapatite Nanocomposites.  |  Fu, LH., et al. 2016. Polymers (Basel). 8: PMID: 30974621
  4. Inorganic Selenium Induces Nonapoptotic Programmed Cell Death in PC-3 Prostate Cancer Cells Associated with Inhibition of Glycolysis.  |  Cui, J., et al. 2019. J Agric Food Chem. 67: 10637-10645. PMID: 31513389
  5. Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters-Ce(III) fluoroprobe.  |  Mei, H., et al. 2021. Anal Bioanal Chem. 413: 2135-2146. PMID: 33511458
  6. Fabrication, Properties, and Biomedical Applications of Calcium-Containing Cellulose-Based Composites.  |  Shi, RJ., et al. 2022. Front Bioeng Biotechnol. 10: 937266. PMID: 35795166
  7. Fructose-1,6-bisphosphate preserves adenosine triphosphate but not intracellular pH during hypoxia in respiring neonatal rat brain slices.  |  Espanol, MT., et al. 1998. Anesthesiology. 88: 461-72. PMID: 9477067

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Fructose 1,6-bisphosphate trisodium salt octahydrate, 1 g

sc-221476
1 g
$57.00

D-Fructose 1,6-bisphosphate trisodium salt octahydrate, 5 g

sc-221476A
5 g
$97.00