Molecular structure of D-(+)-Biotin, CAS Number: 58-85-5
D-(+)-Biotin (CAS 58-85-5)
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Alternate Names:
Vitamin H; 5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid; Biotin
Application:
D-(+)-Biotin is an important ubiquitous metabolism coenzyme
CAS Number:
58-85-5
Purity:
≥98%
Molecular Weight:
244.3
Molecular Formula:
C10H16N2O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-(+)-Biotin is a coenzyme that offers three possible binding sites. It is involved in the regulation of gene transcription through the modification of histones. Additionally, it has applications in biotechnology such as in DNA-hybridization, flow cytometry, affinity purification, and identification of protein-protein interactions and post-translational modifications. Biotin is also used as a growth factor in mammalian cell culture and is essential for cell growth, fatty acid production, and metabolism of fats and amino acids. It is involved in the citric acid cycle and is responsible for transferring carbon dioxide. Furthermore, biotin plays important roles in immunological purification through its avidin/streptavidin-biotin binding mechanisms.
D-(+)-Biotin (CAS 58-85-5) References
- Affinity purification of functional receptors for Escherichia coli heat-stable enterotoxin from rat intestine. | Hugues, M., et al. 1992. Biochemistry. 31: 12-6. PMID: 1310026
- Crystal structure of biotin. | TRAUB, W. 1956. Nature. 178: 649-50. PMID: 13369496
- Density functional theory calculations on the active site of biotin synthase: mechanism of S transfer from the Fe(2)S(2) cluster and the role of 1st and 2nd sphere residues. | Rana, A., et al. 2015. J Biol Inorg Chem. 20: 1147-62. PMID: 26369537
- Capture and Identification of miRNA Targets by Biotin Pulldown and RNA-seq. | Tan, SM. and Lieberman, J. 2016. Methods Mol Biol. 1358: 211-28. PMID: 26463386
- Biotin-conjugated fusogenic liposomes for high-quality cell purification. | Hersch, N., et al. 2016. J Biomater Appl. 30: 846-56. PMID: 26475851
- Immobilized sialyltransferase fused to a fungal biotin-binding protein: Production, properties, and applications. | Kajiwara, H., et al. 2016. J Biosci Bioeng. 121: 390-3. PMID: 26476897
- Biotin-Genomic Run-On (Bio-GRO): A High-Resolution Method for the Analysis of Nascent Transcription in Yeast. | Jordán-Pla, A., et al. 2016. Methods Mol Biol. 1361: 125-39. PMID: 26483020
- Hybrid PET/optical imaging of integrin αVβ3 receptor expression using a (64)Cu-labeled streptavidin/biotin-based dimeric RGD peptide. | Kang, CM., et al. 2015. EJNMMI Res. 5: 60. PMID: 26518424
- Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin. | Soural, M., et al. 2015. Bioconjug Chem. 26: 2563-70. PMID: 26537839
- Synthesis of Cell-Adhesive Anisotropic Multifunctional Particles by Stop Flow Lithography and Streptavidin-Biotin Interactions. | Bong, KW., et al. 2015. Langmuir. 31: 13165-71. PMID: 26545155
- Influence of molecular weight of PEG chain on interaction between streptavidin and biotin-PEG-conjugated phospholipids studied with QCM-D. | Teramura, Y., et al. 2016. Acta Biomater. 30: 135-143. PMID: 26546413
- Fluorescent Biotin Analogues for Microstructure Patterning and Selective Protein Immobilization. | Krishna, KV., et al. 2015. Langmuir. 31: 12573-8. PMID: 26559028
- Biotin-mediated epigenetic modifications: Potential defense against the carcinogenicity of benzo[a]pyrene. | Xia, B., et al. 2016. Toxicol Lett. 241: 216-24. PMID: 26569572
- Phosphopeptide Detection with Biotin-Labeled Phos-tag. | Kinoshita-Kikuta, E., et al. 2016. Methods Mol Biol. 1355: 17-29. PMID: 26584916
- Two-dimensional gel electrophoretic detection of protein carbonyls derivatized with biotin-hydrazide. | Wu, J., et al. 2016. J Chromatogr B Analyt Technol Biomed Life Sci. 1019: 128-31. PMID: 26590475
- A cleavable biotin tagging reagent that enables the enrichment and identification of carbonylation sites in proteins. | Coffey, CM. and Gronert, S. 2016. Anal Bioanal Chem. 408: 865-74. PMID: 26613796
- Biotin enhances guanylate cyclase activity. | Vesely, DL. 1982. Science. 216: 1329-30. PMID: 6123152
- The Structure Of Biotin: A Study Of Desthiobiotin. | Du Vigneaud, V., et al. 1942. Journal of Biological Chemistry. 146: 475-485.
Inhibitor of:
CCDC162, CFDP1, CHIC2, HoxC13, KRTAP1-5, KRTAP2-4, KRTAP4-6, MCCA, PANK3, S-probe, and SBP Tag.Activator of:
α-KGD, β-ketoacyl synthase, δ-FR, 8-oxoG DNA Lesion, AASDHPPT, ACSM4, ACSVL3, ALG3, AMN1, AUH, Avidin, avidin-PE-Cy5, Biotin-NHS, C20orf54, CMAS, cornulin, CPF, D2HGDH, Dim1, DNA pol δ cat, EBP2, ECHDC1, EG628518, Ero1-Lβ, FBP, Formate Dehydrogenase, Fumarylacetoacetase, FUT2, GalNAc-T2, GBP11, GGH, GLDC, HLCS, IDH3A, IDH3B, K12, Keratin 25, Keratin 26, Keratin 27, Keratin 32, Keratin 33A, Keratin 33B, Keratin 35, Keratin 36, Keratin 38, Keratin 72, Keratin 75, Keratin 76, Keratin 79, Keratin 86, KRTAP1, KRTAP1-1, KRTAP1-3, KRTAP1-5, KRTAP10, KRTAP10-10, KRTAP10-11, KRTAP10-2, KRTAP10-5, KRTAP10-6, KRTAP10-7, KRTAP10-8, KRTAP11-1, KRTAP12-4, KRTAP13, KRTAP13-1, KRTAP13-3, KRTAP14, KRTAP16-1, KRTAP16-4, KRTAP16-8, KRTAP16-9, KRTAP17-1, KRTAP19-1, KRTAP19-2, KRTAP19-4, KRTAP19-5, KRTAP19-7, KRTAP19-8, KRTAP2-1, KRTAP20-1, KRTAP20-2, KRTAP21-1, KRTAP21-2, KRTAP22-1, KRTAP24-1, KRTAP26-1, KRTAP3-1, KRTAP3-3, Krtap31-2, KRTAP4, KRTAP4-1, KRTAP4-12, Krtap4-16, KRTAP4-6, KRTAP4-7, Krtap4-9, KRTAP5, KRTAP5-1, KRTAP5-11, KRTAP5-2, KRTAP5-5, KRTAP5-6, KRTAP5-8, KRTAP6-2, KRTAP6-3, KRTAP9-2, Krtap9-5, KRTAP9-8, KRTAP9-L1, KRTAP9-L2, KRTAP9-L3, Lipoic Acid, LIPT1, LOC283398, LOC647264, MBP-probe, MCAT, MCEE, MEM Vitamins, METTL3, NANS, OGDHL, OTA, OTC, PANK1, PANK4, PAP-β, Pax-9, PCCA, PCCB, periaxin, PNPLA1, PNS Myelin, PPC Synthetase, PPC-DC, PRPS2, QDPR, RBKS, RG9MTD1, SMVT_Slc5a6, SQRDL, Streptavidin, Streptavidin- fluorescein, SUCO, Tankyrase-1, TCHHL1, TGase5, TYW1B, UDP-GlcDH, and YTHDF3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-(+)-Biotin, 1 g | sc-204706 | 1 g | $41.00 | |||
D-(+)-Biotin, 5 g | sc-204706A | 5 g | $107.00 | |||
D-(+)-Biotin, 25 g | sc-204706B | 25 g | $333.00 |