Coumarin 1 (CAS 91-44-1)
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Coumarin 1, also 7-(Diethylamino)-4-methylcoumarin, is potentially useful as a laser dye. Coumarin 1 is a fluorescence probe, used in the investigation of hydrogen bond interactions. It can be excited by laser light and emits fluorescent light with a red-shifted wavelength. Analogous to coumarin, this compound contains a hydroxyl group and has demonstrated physiological effects on liver cells. The absorption spectrum of Coumarin 1 shows that its sensitivity to changes in pH and chemical stability. Notably, a decrease in pH intensifies the emission, whereas an increase in pH diminishes it. Additionally, this compound can be used in nucleic acid labeling during polymerase chain reactions (PCR) and sample preparation for nuclear magnetic resonance spectroscopy (NMR) analysis.
Coumarin 1 (CAS 91-44-1) References
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- Pharmacological activities of the prenylcoumarins, developed from folk usage as a medicine of Peucedanum japonicum THUNB. | Takeuchi, N., et al. 1991. Chem Pharm Bull (Tokyo). 39: 1415-21. PMID: 1934161
- Non-covalent interactions of coumarin dyes with cucurbit[7]uril macrocycle: modulation of ICT to TICT state conversion. | Barooah, N., et al. 2012. Org Biomol Chem. 10: 5055-62. PMID: 22618533
- Seasonal variation on the contents of coumarin and kaurane-type diterpenes in Mikania laevigata and M. glomerata leaves under different shade levels. | Bertolucci, SK., et al. 2013. Chem Biodivers. 10: 288-95. PMID: 23418176
- Pressure-Induced Glass Transition Probed via the Mobility of Coumarin 1 Fluorescent Molecule. | Bonetti, M. 2016. J Phys Chem B. 120: 4319-28. PMID: 27110923
- Discovery of Chromen-7-yl Furan-2-Carboxylate as a Potent and Selective Factor XIa Inhibitor. | Obaidullah, AJ. and Al-Horani, RA. 2017. Cardiovasc Hematol Agents Med Chem. 15: 40-48. PMID: 28552062
- New coumarin from the roots of Prangos pabularia. | Numonov, S., et al. 2018. Nat Prod Res. 32: 2325-2332. PMID: 29224384
- Isochronal superpositioning in the equilibrium regime of superpressed propylene carbonate to ∼ 1.8 GPa: A study by diffusivity measurement of the fluorescent probe Coumarin 1. | Bonetti, M. and Dubois, A. 2019. Eur Phys J E Soft Matter. 42: 97. PMID: 31375947
- Photophysical Properties of Coumarin 1 in Bile Salt Aggregates: An Insight into the Role of Bile Salt Structure on the Aggregation Behavior. | Mishra, SS., et al. 2019. Langmuir. 35: 16555-16567. PMID: 31742410
- Anti-Inflammatory and Cytotoxic Potential of New Phenanthrenoids from Luzula Sylvatica. | Gainche, M., et al. 2020. Molecules. 25: PMID: 32443866
- Vibration-Assisted Intersystem Crossing in the Ultrafast Excited-State Relaxation Dynamics of Halocoumarins. | Das, A., et al. 2022. J Phys Chem A. 126: 1475-1485. PMID: 35230832
- New coumarin from the roots of Prangos pabularia growing wild in Tajikistan. | Atolikshoeva, S., et al. 2022. Nat Prod Res. 1-9. PMID: 35895127
- Novel Formulations Containing Fluorescent Sensors to Improve the Resolution of 3D Prints. | Topa-Skwarczyńska, M., et al. 2022. Int J Mol Sci. 23: PMID: 36142382
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Coumarin 1, 250 mg | sc-294102 | 250 mg | $61.00 | |||
Coumarin 1, 500 mg | sc-294102A | 500 mg | $72.00 |