Copper (II) acetate monohydrate Used in biochemical applications such as DNA extraction

Copper (II) acetate monohydrate (CAS 6046-93-1)

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Application: Used in biochemical applications such as DNA extraction
CAS Number: 6046-93-1
Molecular Weight: 199.65
Molecular Formula: Cu(C2H3O2)2 H2O
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Copper(II) acetate monohydrate is used in biochemical applications such as DNA extraction. Copper(II) complexes have been evaluated for anticancer, antibacterial and antifungal activities. Cu(II) complexes are known to cleave DNA; however, increased efficiency is seen in the presence of an oxidizer (often H2O2). Copper acetate exists in a dimeric structure in the solid state as well as in non-aqueous solution. Has been shown to bind the ribose hydroxyls of both purine and pyrimidine nucleosides. Popular methods for DNA extraction may be hindered by endogenous levels of polysaccharides, phenolics and other organic molecules; Copper(II) acetate treatment has been shown to fix and remove tannins in samples from Pyrus (Pear) yielding high quality DNA.


1. Devereux, M., et al. 2004. J. Inorg. Biochem. 98: 1023-1031. PMID: 15149811
2. Berger, N.A., et al. 1972. Nature New Biol. 239: 237-240. PMID: 4538853
3. Fewster, M.E., et al. 1969. J Chromatogr. 43:120-126. PMID: 5802175

Appearance :
Physical State :
Solubility :
Soluble in water (72 mg/ml at 20° C), alcohol, ether (slightly), and glycerin (slightly).
Storage :
Store at room temperature
Melting Point :
115° C
Boiling Point :
240° C
Density :
1.88 g/cm3 at 20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 2624
MDL Number :
EC Number :
Beilstein Registry :

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