Clinafloxacin Hydrochloride An antimicrobial fluoroquinolone which inhibits topoisomerase IV

Clinafloxacin Hydrochloride (CAS 105956-99-8)

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Synonym: 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride
Application: An antimicrobial fluoroquinolone which inhibits topoisomerase IV
CAS Number: 105956-99-8
Purity: ≥99%
Molecular Weight: 402.25
Molecular Formula: C17H17ClFN3O3•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Clinafloxacin hydrochlorideis an antimicrobial fluoroquinolone which inhibits topoisomerase IV.


References

Pan, X.S., Fisher, L.M. Antimicrob Agents Chemother. 43:1129-36 (1999)

Physical State :
Solid
Solubility :
Soluble in methanol (~2 mg/ml at 25° C), and water.
Storage :
Store at room temperature
Melting Point :
>150° C (dec.)
Boiling Point :
592.3° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
IC50 :
Streptokinase A: EC5050 = 64 nM (Streptococcus pyogenes serotype M1); Streptococcus sp. 'group A': EC5050 = 115 nM; Streptococcus: EC5050 = 142 nM; DNA gyrase: IC50 = 0.55 µM (Escherichia coli K-12); V79: IC50 = 71.08 µM (Cricetulus griseus)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
60062
MDL Number :
MFCD03840545
SMILES :
C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)Cl)N4CCC(C4)N)F)C(=O)O.Cl

Download SDS (MSDS)

Certificate of Analysis

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