Date published: 2026-2-25

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cis-4-Hydroxycinnamic acid (CAS 4501-31-9)

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Alternate Names:
(2Z)-3-(4-Hydroxyphenyl)-2-propenoic Acid; (Z)-3-(4-hydroxyphenyl)-2-propenoic Acid
CAS Number:
4501-31-9
Molecular Weight:
164.16
Molecular Formula:
C9H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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cis-4-Hydroxycinnamic acid is a compound of interest in the fields of organic chemistry and plant biochemistry. It is studied for its role in plant metabolism and as an intermediate in the biosynthesis of flavonoids and related phenolic compounds, which are important for plant defense mechanisms. In organic chemistry research, cis-4-Hydroxycinnamic acid is used to investigate the properties of cinnamic acid derivatives, including their reactivity and potential as precursors for the synthesis of more complex organic molecules. The compound is also involved in studies of photochemistry, where cis-trans isomerization can be induced by light exposure, providing insights into the behavior of stilbene-like compounds under various conditions. Additionally, cis-4-Hydroxycinnamic acid is used in the synthesis of liquid crystals and other materials, where the influence of the cis configuration on molecular packing and material properties is of particular interest. Its role in the formation of crosslinking structures in polymer matrices is another area of application, exploring the potential of enhancing material strength and stability.


cis-4-Hydroxycinnamic acid (CAS 4501-31-9) References

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  3. The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, alpha-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane.  |  Tarzi, OI., et al. 2009. J Mass Spectrom. 44: 260-77. PMID: 19012278
  4. Unravelling the Structural and Molecular Basis Responsible for the Anti-Biofilm Activity of Zosteric Acid.  |  Cattò, C., et al. 2015. PLoS One. 10: e0131519. PMID: 26132116
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cis-4-Hydroxycinnamic acid, 50 mg

sc-490553
50 mg
$800.00

cis-4-Hydroxycinnamic acid, 100 mg

sc-490553A
100 mg
$1230.00

cis-4-Hydroxycinnamic acid, 250 mg

sc-490553B
250 mg
$2046.00

cis-4-Hydroxycinnamic acid, 500 mg

sc-490553C
500 mg
$3066.00